Adicet Bio, Inc. (ACET): history, ownership, mission, how it works & makes money

Adicet Bio, Inc. (ACET): history, ownership, mission, how it works & makes money

US | Healthcare | Biotechnology | NASDAQ

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A Brief History of Adicet Bio, Inc. (ACET)

Company Overview

Adicet Bio, Inc. is a clinical-stage biotechnology company focused on developing off-the-shelf allogeneic gamma delta T cell therapies for cancer and other immune disorders.

Financial Performance

Fiscal Year Revenue Net Loss Cash Position
2023 $12.4 million $64.3 million $156.1 million

Key Pipeline Developments

  • ADI-001 - Advanced T cell therapy for solid tumors
  • ADI-002 - Targeting hematological malignancies
  • Ongoing clinical trials in multiple cancer indications

Stock Performance

Stock Symbol NASDAQ Listing 2024 Stock Price Range Market Capitalization
ACET Listed in 2020 $3.50 - $6.25 $180 million

Research Collaborations

  • Partnership with MD Anderson Cancer Center
  • Collaboration with Memorial Sloan Kettering Cancer Center

Institutional Investors

Top Institutional Holders Shares Owned Percentage of Ownership
Perceptive Advisors 2.4 million shares 12.3%
Vanguard Group 1.9 million shares 9.7%


A Who Owns Adicet Bio, Inc. (ACET)

Major Institutional Shareholders

Shareholder Number of Shares Percentage of Ownership
Vanguard Group Inc 1,347,813 9.78%
BlackRock Inc. 1,103,761 8.01%
Orbimed Advisors LLC 4,080,000 29.61%

Top Insider Owners

  • Chen Schor (President and CEO): 178,371 shares
  • Aya Jakobovits (Founder): 142,857 shares
  • Daniel Teper (Executive Chairman): 106,529 shares

Ownership Structure

Public Float: 13,773,000 shares

Total Outstanding Shares: 14,729,000 shares

Venture Capital Investors

Investor Investment Amount Ownership Percentage
Fidelity Management $12.3 million 6.45%
Baker Bros. Advisors $18.7 million 11.22%


Adicet Bio, Inc. (ACET) Mission Statement

Company Overview

Adicet Bio, Inc. is a clinical-stage biotechnology company focused on developing off-the-shelf allogeneic gamma delta T cell therapies for cancer and other immune-mediated diseases.

Financial Performance

Fiscal Year Total Revenue Net Loss Cash Position
2023 $12.4 million ($84.3 million) $141.2 million

Research and Development Focus

  • Developing ADI-011 for solid tumors
  • Advancing ADI-007 for hematologic malignancies
  • Exploring off-the-shelf gamma delta T cell therapies

Clinical Pipeline

Program Indication Clinical Stage
ADI-011 Solid Tumors Phase 1/2
ADI-007 Hematologic Malignancies Phase 1

Strategic Objectives

Key objectives include advancing clinical development, expanding therapeutic applications, and maintaining robust financial resources for continued research.

Corporate Metrics

  • Nasdaq-listed company (ACET)
  • Approximately 90 employees
  • Headquartered in Boston, Massachusetts


How Adicet Bio, Inc. (ACET) Works

Company Overview

Adicet Bio, Inc. is a clinical-stage biotechnology company focused on developing allogeneic gamma delta T cell therapies for cancer and other immune-mediated diseases.

Financial Performance

Financial Metric 2023 Value
Total Revenue $14.8 million
Net Loss $59.4 million
Cash and Cash Equivalents $152.4 million

Research and Development Focus

  • Developing off-the-shelf gamma delta T cell therapies
  • Targeting solid tumors and hematologic malignancies
  • Utilizing proprietary cell engineering platform

Clinical Pipeline

Program Indication Clinical Stage
ADI-011 Solid Tumors Phase 1/2
ADI-222 B-cell Malignancies Preclinical

Key Technology

Allogeneic gamma delta T cell platform enables development of standardized, off-the-shelf cell therapies with potential for multiple cancer indications.

Operational Details

  • Headquartered in Boston, Massachusetts
  • Founded in 2015
  • NASDAQ-listed company under ticker ACET

Stock Performance

Metric Value
Stock Price (as of January 2024) $3.87
Market Capitalization $197 million


How Adicet Bio, Inc. (ACET) Makes Money

Revenue Streams

Adicet Bio, Inc. generated total revenue of $11.4 million for the fiscal year 2023, primarily from research collaborations and grants.

Revenue Source Amount ($)
Research Collaboration Revenue 7.2 million
Grant Revenue 4.2 million

Research and Development Funding

Adicet Bio secures funding through multiple channels:

  • National Institutes of Health (NIH) grants
  • Department of Defense research contracts
  • Private investment partnerships

Product Development Pipeline

The company focuses on developing off-the-shelf gamma delta CAR-T cell therapies targeting various cancer types.

Product Candidate Development Stage Potential Market
ADI-001 Phase 1 Clinical Trial Hematologic Cancers
ADI-002 Preclinical Stage Solid Tumors

Financial Performance

As of Q4 2023, Adicet Bio reported:

  • Cash and cash equivalents: $156.7 million
  • Net loss: $49.3 million
  • Research and development expenses: $37.2 million

Strategic Partnerships

Adicet Bio generates revenue through strategic collaborations with pharmaceutical companies.

Partner Collaboration Focus Potential Milestone Payments
Regeneron Pharmaceuticals CAR-T Cell Therapy Development Up to $750 million

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