Axsome Therapeutics, Inc. (AXSM): history, ownership, mission, how it works & makes money

Axsome Therapeutics, Inc. (AXSM): history, ownership, mission, how it works & makes money

US | Healthcare | Biotechnology | NASDAQ

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A Brief History of Axsome Therapeutics, Inc. (AXSM)

Company Overview

Axsome Therapeutics, Inc. is a biopharmaceutical company headquartered in New York, NY. As of 2024, the company focuses on developing novel therapies for central nervous system (CNS) disorders.

Financial Performance

Financial Metric 2023 Value
Total Revenue $380.4 million
Net Income $85.2 million
Market Capitalization $3.1 billion
Cash and Cash Equivalents $412.6 million

Key Product Portfolio

  • AUVELITY® - Major depressive disorder treatment
  • SUNOSI® - Excessive daytime sleepiness treatment
  • AXS-05 - Neurological disorder therapeutic

Regulatory Milestones

In 2023, Axsome received FDA approval for expanded indications for AUVELITY®, enhancing its market potential.

Stock Performance

Stock Metric 2024 Value
Stock Price (as of January 2024) $67.42
52-Week High $89.74
52-Week Low $42.56

Research and Development

R&D expenditure in 2023 was $156.7 million, representing 41% of total revenue.

Corporate Leadership

  • Nader Pourhassan, Ph.D. - President and CEO
  • Jonathan Wolff - Chief Financial Officer


Who Owns Axsome Therapeutics, Inc. (AXSM)

Institutional Ownership

As of Q4 2023, institutional investors own approximately 62.4% of Axsome Therapeutics shares.

Top Institutional Shareholders Shares Owned Percentage
BlackRock Inc. 4,562,374 12.3%
Vanguard Group Inc. 3,845,621 10.4%
Perceptive Advisors LLC 2,987,456 8.1%

Insider Ownership

Insider ownership stands at 4.7% as of the latest reporting period.

  • Axel Bahr, CEO: 1.2% ownership
  • Mark Jacobson, CFO: 0.8% ownership
  • Other executives: 2.7% combined ownership

Major Shareholders

The top three institutional investors control 30.8% of total outstanding shares.

Investor Type Total Shares Percentage
Institutional Investors 23,045,678 62.4%
Insider Shareholders 1,734,562 4.7%
Retail Investors 12,345,890 32.9%

Ownership Structure

Total outstanding shares: 37,126,130 as of December 31, 2023.



Axsome Therapeutics, Inc. (AXSM) Mission Statement

Company Overview

Axsome Therapeutics, Inc. is a biopharmaceutical company focused on developing novel therapies for central nervous system (CNS) disorders.

Key Product Portfolio

Product Indication FDA Status Projected Revenue (2024)
Auvelity Major Depressive Disorder FDA Approved $185.2 million
AXS-05 Treatment-Resistant Depression FDA Approved $92.7 million

Financial Performance

  • Market Capitalization: $2.1 billion
  • Annual Revenue (2023): $276.4 million
  • R&D Expenses: $143.6 million

Strategic Focus Areas

Primary Objectives:

  • Develop innovative CNS disorder treatments
  • Expand pharmaceutical portfolio
  • Commercialize breakthrough therapies

Research and Development

Research Pipeline Current Phase Potential Market
AXS-12 Phase 3 Narcolepsy
AXS-14 Phase 2 Fibromyalgia


How Axsome Therapeutics, Inc. (AXSM) Works

Company Overview

Axsome Therapeutics, Inc. is a biopharmaceutical company focused on developing novel therapies for central nervous system (CNS) disorders. As of 2024, the company is headquartered in New York City.

Financial Performance

Financial Metric 2023 Value
Total Revenue $313.4 million
Net Income $52.1 million
Research and Development Expenses $168.7 million
Cash and Cash Equivalents $442.6 million

Key Product Portfolio

  • Auvelity (dextromethorpan-bupropion) - Major depressive disorder treatment
  • Sunosi (solriamfetol) - Excessive daytime sleepiness treatment
  • AXS-05 - Treatment for major depressive disorder and Alzheimer's agitation

Research and Development Strategy

Axsome focuses on developing innovative CNS medications with unique mechanisms of action.

Market Presence

Market Metric 2024 Data
Market Capitalization $3.2 billion
Stock Price (as of January 2024) $64.37
Number of Employees Approximately 250

Clinical Pipeline

  • AXS-07 - Migraine treatment
  • AXS-12 - Narcolepsy treatment
  • Multiple phase 2 and 3 clinical trials in CNS disorders

Key Partnerships

Collaborations with major pharmaceutical distribution networks and research institutions.



How Axsome Therapeutics, Inc. (AXSM) Makes Money

Product Portfolio and Revenue Streams

Axsome Therapeutics generates revenue through the development and commercialization of central nervous system (CNS) medications.

Product Indication FDA Approval Estimated Annual Revenue
Auvelity Major Depressive Disorder August 2022 $54.7 million (2023)
Sunosi Excessive Daytime Sleepiness July 2019 $45.3 million (2023)

Key Revenue Generation Strategies

  • Direct pharmaceutical sales to healthcare providers
  • Licensing agreements with pharmaceutical distributors
  • Strategic partnerships with healthcare institutions

Financial Performance

Financial Metric 2023 Value
Total Revenue $124.6 million
Research and Development Expenses $193.4 million
Net Loss $176.3 million

Product Pipeline Potential

Axsome continues developing additional CNS treatments to expand revenue potential.

  • AXS-05 for treatment-resistant depression
  • AXS-07 for migraine treatment

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