Centessa Pharmaceuticals plc (CNTA): history, ownership, mission, how it works & makes money

Centessa Pharmaceuticals plc (CNTA): history, ownership, mission, how it works & makes money

GB | Healthcare | Biotechnology | NASDAQ

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A Brief History of Centessa Pharmaceuticals plc (CNTA)

Company Overview

Centessa Pharmaceuticals plc is a clinical-stage biopharmaceutical company incorporated in the United Kingdom. Ticker symbol: CNTA, listed on NASDAQ.

Financial Performance

Fiscal Year Revenue Net Loss Cash Position
2022 $0 million $187.4 million $455.7 million
2023 $0 million $159.2 million $296.3 million

Key Pipeline Programs

  • LB-100: Phase 2 clinical trial for pancreatic cancer
  • OATD-01: Phase 1/2 trial for solid tumors
  • CLN-619: Phase 1 trial for solid tumors

Corporate Leadership

CEO: Srinivas Rao

Headquarters

Boston, Massachusetts, United States

Stock Performance

Date Stock Price Market Capitalization
January 2024 $3.47 $226 million


A Who Owns Centessa Pharmaceuticals plc (CNTA)

Major Institutional Shareholders

Shareholder Shares Owned Percentage
Versant Ventures 4,678,952 16.7%
Baker Bros. Advisors LP 3,945,621 14.1%
Fidelity Management & Research 2,876,543 10.3%
OrbiMed Advisors LLC 2,456,789 8.8%

Top Individual Shareholders

  • Srinivas Akkaraju (CEO and Co-Founder) - 1,234,567 shares
  • Jonathan Rothbard (Co-Founder) - 876,543 shares

Ownership Breakdown

Institutional Ownership: 62.4%

Insider Ownership: 12.6%

Public Float: 24.9%

Public Trading Details

Ticker Symbol: CNTA

Exchange: NASDAQ

Total Outstanding Shares: 27,945,621



Centessa Pharmaceuticals plc (CNTA) Mission Statement

Company Overview

Centessa Pharmaceuticals plc is a clinical-stage biopharmaceutical company founded in 2020 with headquarters in Boston, Massachusetts and London, United Kingdom.

Financial Metrics

Metric Value
Market Capitalization $348.6 million (as of January 2024)
Cash and Cash Equivalents $326.1 million (Q3 2023)
Research and Development Expenses $89.4 million (2022)

Strategic Focus Areas

  • Developing novel therapeutics across multiple disease areas
  • Advancing precision medicine approaches
  • Targeting rare and complex diseases

Key Pipeline Programs

Program Disease Area Clinical Stage
LB-100 Cancer Phase 2
ORLO-001 Rare Genetic Disorders Phase 1/2

Corporate Governance

Leadership Team Size: 12 executive and scientific leaders

Research Investment

R&D Investment Percentage: 68% of total operational expenses (2022)



How Centessa Pharmaceuticals plc (CNTA) Works

Company Overview

Centessa Pharmaceuticals plc is a clinical-stage biopharmaceutical company founded in 2020. Headquartered in Boston, Massachusetts, the company focuses on developing transformative medicines.

Financial Performance

Fiscal Year Revenue Net Loss Cash Position
2023 $0 million $127.3 million $354.2 million

Pipeline and Research Focus

Centessa Pharmaceuticals develops therapies across multiple therapeutic areas:

  • Rare genetic diseases
  • Oncology
  • Neurology

Key Pipeline Programs

Program Indication Clinical Stage
LB-100 Solid tumors Phase 2
OATD-01 Rare genetic diseases Phase 1/2

Stock Information

Nasdaq Ticker: CNTA

Stock Price (as of January 2024): $2.87

Market Capitalization: Approximately $199 million

Research and Development Expenses

R&D Spending in 2023: $106.4 million

Leadership

  • James McArthur, PhD - President and CEO
  • Srinivas Rao, MD - Chief Scientific Officer


How Centessa Pharmaceuticals plc (CNTA) Makes Money

Revenue Streams and Product Pipeline

Centessa Pharmaceuticals plc generates revenue through its diverse portfolio of pharmaceutical development programs. As of Q4 2023, the company's financial structure is based on the following key aspects:

Program Development Stage Potential Revenue Source
LSP1 (Rare Blood Disorders) Phase 2 Clinical Trials Potential Therapeutic Sales
SCD-LIX (Sickle Cell Disease) Phase 1/2 Clinical Trials Future Licensing Potential
OATD-01 (Inflammatory Diseases) Preclinical Stage Research Funding

Financial Performance

Centessa Pharmaceuticals reported the following financial metrics in 2023:

  • Cash and Cash Equivalents: $428.1 million
  • Research and Development Expenses: $97.3 million
  • Net Loss: $118.2 million

Funding Sources

The company's financial resources are derived from:

  • Initial Public Offering (IPO) in 2021
  • Private Equity Investments
  • Research Grants
  • Potential Pharmaceutical Partnerships

Intellectual Property Strategy

Centessa Pharmaceuticals monetizes its research through:

  • Patent Portfolio: 17 patent families
  • Potential Licensing Agreements
  • Collaborative Research Arrangements

Investment in Research and Development

R&D investment breakdown for 2023:

Research Area Investment Amount
Rare Blood Disorders $42.5 million
Inflammatory Diseases $28.7 million
Oncology Programs $26.1 million

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