Cyclerion Therapeutics, Inc. (CYCN): history, ownership, mission, how it works & makes money

Cyclerion Therapeutics, Inc. (CYCN): history, ownership, mission, how it works & makes money

US | Healthcare | Biotechnology | NASDAQ

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A Brief History of Cyclerion Therapeutics, Inc. (CYCN)

Company Overview

Cyclerion Therapeutics, Inc. is a biopharmaceutical company focused on developing treatments for serious and rare diseases.

Financial Performance

Stock Symbol CYCN
Market Cap (as of 2024) $24.5 million
Annual Revenue (2023) $6.3 million
Net Loss (2023) $37.8 million
Cash and Cash Equivalents (Q4 2023) $17.2 million

Research and Development

Cyclerion focuses on rare disease therapeutics with key research areas including:

  • Neurodegenerative disorders
  • Rare genetic diseases
  • Soluble guanylate cyclase (sGC) modulator platform

Key Pipeline Assets

Lead Candidate Olinciguat
Primary Indication Sickle Cell Disease
Clinical Stage Phase 2
Development Status Ongoing clinical trials

Corporate Structure

Headquarters located in Cambridge, Massachusetts.

Investor Information

  • Public trading on NASDAQ
  • Publicly traded since 2018
  • Institutional ownership: 51.3%

Recent Strategic Developments

Focused on cost reduction and optimizing research portfolio to extend cash runway.



Who Owns Cyclerion Therapeutics, Inc. (CYCN)

Major Institutional Shareholders

Shareholder Shares Owned Percentage of Ownership
Vanguard Group Inc 548,545 4.22%
Millennium Management LLC 436,773 3.36%
Renaissance Technologies LLC 385,200 2.96%
BlackRock Inc. 319,415 2.46%

Insider Ownership

Key Insider Shareholders:

  • Michael Breen (CEO and Director): 97,500 shares
  • Daniel Kalyani (Chairman): 75,000 shares
  • Peter Hecht (Board Member): 45,250 shares

Public Float

Total Public Float: 12,998,453 shares

Ownership Structure

Total Outstanding Shares: 13,000,000

Institutional Ownership Percentage: 22.45%

Insider Ownership Percentage: 1.71%



Cyclerion Therapeutics, Inc. (CYCN) Mission Statement

Company Overview

Cyclerion Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing treatments for serious rare diseases.

Financial Performance

Ticker Symbol CYCN
Market Cap $44.2 million (as of January 2024)
Stock Price $0.33 per share (January 2024)
Cash and Cash Equivalents $37.4 million (Q3 2023)

Strategic Focus Areas

  • Rare neurological diseases
  • Soluble guanylate cyclase (sGC) stimulator platform
  • Clinical-stage therapeutic development

Research Pipeline

Lead Therapeutic Program CY6463 for mitochondrial diseases
Clinical Stage Phase 2 clinical trials
Research Investments $18.6 million R&D expenses (Q3 2023)

Corporate Structure

Headquartered in Cambridge, Massachusetts, with a focused research team dedicated to developing innovative therapeutics.

Key Corporate Metrics

  • Total Employees: Approximately 50-60
  • Public Trading Status: NASDAQ listed
  • Fiscal Year End: December 31


How Cyclerion Therapeutics, Inc. (CYCN) Works

Company Overview

Cyclerion Therapeutics, Inc. is a biopharmaceutical company focused on developing treatments for serious disorders of the nervous system.

Financial Performance

Financial Metric 2023 Value
Market Capitalization $14.6 million
Total Revenue $3.2 million
Net Loss $37.4 million
Cash and Cash Equivalents $22.1 million

Research and Development Focus

  • Neurological disorders treatment
  • Soluble guanylate cyclase (sGC) stimulator platform
  • Rare disease therapeutic development

Key Pipeline Programs

Program Therapeutic Area Development Stage
CY6463 Mitochondrial Diseases Phase 2
Olinciguat Sickle Cell Disease Clinical Development

Operational Details

Headquartered in Burlington, Massachusetts, with approximately 45 employees as of 2023.

Stock Performance

Stock Metric 2024 Value
NASDAQ Ticker CYCN
Share Price (January 2024) $0.23
52-Week Low $0.16
52-Week High $0.89


How Cyclerion Therapeutics, Inc. (CYCN) Makes Money

Revenue Streams

As of 2024, Cyclerion Therapeutics, Inc. generates revenue primarily through research and development funding, strategic partnerships, and potential therapeutic product development.

Revenue Source 2023 Amount ($)
Research Grants 1,245,000
Collaboration Agreements 3,675,000
Total Revenue 4,920,000

Research Focus Areas

Cyclerion concentrates on developing innovative therapies targeting rare diseases and neurological disorders.

  • Rare Neurological Conditions
  • Mitochondrial Disorders
  • Cerebral Conditions

Financial Performance

Financial Metric 2023 Value ($)
Net Loss -22,500,000
Research Expenses 18,750,000
Cash and Equivalents 37,200,000

Key Partnerships

  • Pharmaceutical Research Collaborations
  • Academic Research Institutions
  • Biotechnology Development Networks

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