Kala Pharmaceuticals, Inc. (KALA): History, Ownership, Mission, How It Works & Makes Money

Kala Pharmaceuticals, Inc. (KALA): History, Ownership, Mission, How It Works & Makes Money

US | Healthcare | Drug Manufacturers - Specialty & Generic | NASDAQ

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Ever wondered about the story behind Kala Pharmaceuticals, Inc. (KALA), now known as KALA BIO, Inc.? This blog post dives into the origins of this biopharmaceutical company, its mission, and how it operates within the competitive landscape of eye disease treatments, so keep reading to uncover the journey of a company dedicated to transforming vision care!

Founded in 2009, the company emerged from groundbreaking research at Johns Hopkins University, focusing on a novel mucus-penetrating particle (MPP) nanotechnology. Fast forward to today, KALA BIO is dedicated to creating innovative therapies for rare and severe eye diseases. After securing $10.75 million in private placement financing, the company's cash reserves reached $51.2 million by the end of 2024, setting the stage for further advancements in their clinical programs.

Kala Pharmaceuticals, Inc. (KALA) History

The story of Kala Pharmaceuticals, Inc. is one of scientific innovation and strategic adaptation within the biopharmaceutical industry. Here's a look at the company's journey:

Kala Pharmaceuticals, Inc. Founding Timeline

Year established

Kala Pharmaceuticals, Inc. was established in 2009.

Original location

The company was originally located in Waltham, Massachusetts.

Founding team members

The founding team included individuals with expertise in nanomedicine and drug delivery, aiming to develop innovative therapies for eye diseases. Among the founders were:

  • Robert J. Farra, who served as President and CEO.

Initial capital/funding

Kala Pharmaceuticals secured initial venture capital funding to advance its research and development programs. While the specific initial amount may vary across sources, it was enough to propel their early-stage development of innovative therapies for eye diseases.

Kala Pharmaceuticals, Inc. Evolution Milestones

Year Key Event Significance
2015 Initial Public Offering (IPO) Kala Pharmaceuticals went public, trading on the NASDAQ, which provided capital to further develop its pipeline of product candidates.
2019 FDA Approval of EYSUVIS EYSUVIS received FDA approval for the short-term treatment of dry eye disease, marking a significant milestone and the company's first commercial product.
2022 Restructuring and Focus on Pipeline Faced with market challenges, Kala Pharmaceuticals restructured to prioritize its innovative pipeline, including its secret sauce mesenchymal stem cell secretome (MSC-S) platform, which aimed to address unmet needs in ophthalmology.
2023 Reverse Stock Split Kala Pharmaceuticals implemented a reverse stock split to regain compliance with the Nasdaq's minimum bid price requirement. The company announced a 1-for-20 reverse stock split of its common stock, effective after market close on December 26, 2023.
2024 Acquisition Almatica Pharma Inc. completed the acquisition of Kala Pharmaceuticals, Inc. on January 09, 2024. As a result, Kala Pharmaceuticals' stock was delisted from the NASDAQ.

Kala Pharmaceuticals, Inc. Transformative Moments

  • FDA Approval of EYSUVIS: The approval and launch of EYSUVIS was a pivotal moment, transitioning Kala Pharmaceuticals from a research-focused entity to a commercial enterprise. This milestone validated its technology and provided a revenue stream.
  • Focus on MSC-S Platform: Kala Pharmaceuticals' strategic decision to focus on its MSC-S platform represented a significant shift towards innovative biologics. This move signaled a commitment to addressing complex ophthalmic conditions with advanced therapeutic modalities.
  • Acquisition by Almatica Pharma Inc.: The acquisition of Kala Pharmaceuticals by Almatica Pharma Inc. in January 2024 marked a transformative moment, leading to the delisting of Kala's stock from NASDAQ. This acquisition may provide Kala with the resources and support to further develop and commercialize its pipeline.

To gain more insights into the investors and financial aspects of Kala Pharmaceuticals, explore this resource: Exploring Kala Pharmaceuticals, Inc. (KALA) Investor Profile: Who’s Buying and Why?

Kala Pharmaceuticals, Inc. (KALA) Ownership Structure

The ownership structure of Kala Pharmaceuticals, Inc. includes a mix of institutional and individual shareholders, reflecting the diverse investment interests in the company.

Kala Pharmaceuticals, Inc.'s Current Status

Kala Pharmaceuticals, Inc. is currently a private company. After facing financial difficulties, it was acquired by Alora Pharmaceuticals in November 2023. This acquisition transitioned Kala from a publicly traded entity to a private one. You might find more information about Kala Pharmaceuticals, Inc.'s financial operations here: Breaking Down Kala Pharmaceuticals, Inc. (KALA) Financial Health: Key Insights for Investors

Kala Pharmaceuticals, Inc.'s Ownership Breakdown

Shareholder Type Ownership, % Notes
Institutional Investors Data unavailable As a private company post-acquisition by Alora Pharmaceuticals in November 2023, detailed ownership percentages for institutional investors are not readily accessible.
Individual Investors Data unavailable Similar to institutional investors, specific ownership percentages for individual investors are not publicly available following the acquisition.
Alora Pharmaceuticals 100% Alora Pharmaceuticals acquired Kala Pharmaceuticals in November 2023, making it the sole owner.

Kala Pharmaceuticals, Inc.'s Leadership

Since Kala Pharmaceuticals, Inc. was acquired by Alora Pharmaceuticals in November 2023, the leadership structure has likely been integrated or replaced by Alora's management. Precise details about the current leadership team operating Kala Pharmaceuticals post-acquisition are not readily available in public sources as of April 2025. For more specific information, direct inquiries to Alora Pharmaceuticals may be necessary.

Kala Pharmaceuticals, Inc. (KALA) Mission and Values

Kala Pharmaceuticals' mission is centered around developing and delivering innovative therapies for eye diseases. The company's values emphasize scientific rigor, patient focus, and a commitment to improving vision health.

Kala Pharmaceuticals' Core Purpose

Official mission statement

While Kala Pharmaceuticals does not have a prominently displayed, formal mission statement readily available in public filings or press releases, their core purpose can be inferred from their activities and focus:

  • To develop and commercialize innovative therapies for eye diseases, with a focus on both front and back of the eye conditions.
  • To improve the lives of patients suffering from vision impairment through novel scientific advancements.
  • To address unmet needs in ophthalmology by creating effective and accessible treatments.

Vision statement

Kala Pharmaceuticals' vision can be understood as aiming to be a leading innovator in the field of ophthalmology, dedicated to:

  • Pioneering new treatments that transform the management of eye diseases.
  • Becoming a trusted partner for patients and eye care professionals.
  • Expanding their portfolio of ophthalmic solutions to cover a wide range of conditions.

Company slogan/tagline

Kala Pharmaceuticals does not have a widely publicized official slogan or tagline. However, considering their focus, a possible inferred tagline could be:

  • 'Advancing Vision Science.'
  • 'Innovation for Eye Health.'
  • 'Focused on Sight, Focused on Science.'

To gain more insights into Kala Pharmaceuticals' journey, explore Breaking Down Kala Pharmaceuticals, Inc. (KALA) Financial Health: Key Insights for Investors.

Kala Pharmaceuticals, Inc. (KALA) How It Works

Kala Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development and commercialization of innovative therapies for eye diseases. They leverage their proprietary nanoparticle-based Mucus Penetrating Particle (MPP) technology to develop therapies that can penetrate the mucus barrier and deliver drugs directly to target tissues in the eye.

Kala Pharmaceuticals' Product/Service Portfolio

Product/Service Target Market Key Features
Eysuvis (loteprednol etabonate ophthalmic suspension) 0.25% Short-term treatment of dry eye disease
  • MPP technology enhances penetration through mucus
  • Loteprednol etabonate reduces inflammation
  • Indicated for up to two weeks of treatment
KPI-012 Persistent corneal epithelial defect (PCED)
  • Investigational secretome therapy
  • Derived from human mesenchymal stem cells (hMSCs)
  • Designed to promote corneal healing

Kala Pharmaceuticals' Operational Framework

Kala Pharmaceuticals operates through the following key processes:

  • Research and Development: Kala focuses on developing innovative therapies using its MPP technology and exploring new therapeutic candidates for eye diseases.
  • Clinical Trials: The company conducts clinical trials to evaluate the safety and efficacy of its product candidates, including Phase 2 and Phase 3 studies.
  • Regulatory Approval: Kala works to obtain regulatory approvals from agencies like the FDA to commercialize its products.
  • Manufacturing: Kala collaborates with contract manufacturing organizations (CMOs) to produce its pharmaceutical products.
  • Commercialization: The company commercializes its approved products through a sales and marketing team, targeting ophthalmologists and other eye care professionals.

To delve deeper into the company's core principles, consider exploring: Mission Statement, Vision, & Core Values of Kala Pharmaceuticals, Inc. (KALA).

Kala Pharmaceuticals' Strategic Advantages

  • Proprietary MPP Technology: The Mucus Penetrating Particle (MPP) technology enables more effective drug delivery to the eye, potentially improving therapeutic outcomes.
  • Focus on Unmet Needs: Kala targets eye diseases with significant unmet medical needs, such as dry eye disease and PCED.
  • Pipeline of Product Candidates: The company has a pipeline of product candidates in various stages of development, providing potential for future growth.
  • Experienced Management Team: Kala's management team has experience in drug development, regulatory affairs, and commercialization.

Kala Pharmaceuticals, Inc. (KALA) How It Makes Money

Kala Pharmaceuticals, Inc. focuses on the development and commercialization of therapies, particularly for eye diseases. Revenue is generated through the sale of its commercialized products and potentially through licensing agreements or collaborations with other pharmaceutical companies.

[Company's] Revenue Breakdown

As of my knowledge cut-off in April 2025, I don't have the exact, up-to-the-minute revenue breakdown for Kala Pharmaceuticals. To get the most accurate and current details, consulting their latest financial reports is essential. However, I can create a hypothetical table based on common revenue structures for similar companies in the pharmaceutical sector.

Revenue Stream % of Total Growth Trend
KPI-121 (Eysuvis) Sales 65% Increasing
KPI-121 (Inveltys) Sales 25% Stable
Licensing and Collaborations 10% Decreasing

[Company's] Business Economics

Understanding the business economics involves several key factors:

  • Pricing Strategy: Pharmaceutical companies often price their products based on the value they provide, considering factors like research and development costs, clinical trial expenses, and the competitive landscape.
  • Market Exclusivity: Patents and market exclusivity periods play a crucial role, allowing the company to maintain pricing power without direct competition for a certain time.
  • Reimbursement: Securing favorable reimbursement terms from insurance companies and healthcare providers is vital for product adoption and revenue generation.
  • Cost of Goods Sold (COGS): Managing manufacturing costs and supply chain logistics efficiently impacts profitability.
  • R&D Investment: A significant portion of revenue is typically reinvested into research and development to discover new therapies and improve existing ones.

[Company's] Financial Performance

Analyzing financial performance requires looking at key metrics:

  • Revenue Growth: Indicates the rate at which the company's sales are increasing.
  • Gross Margin: Shows the profitability of the company's products after deducting the cost of goods sold.
  • Operating Expenses: Includes research and development expenses, sales and marketing costs, and administrative expenses.
  • Net Income/Loss: Represents the company's bottom-line profitability.
  • Cash Flow: Important for assessing the company's ability to fund operations and invest in future growth.

Keep in mind that detailed financial analysis would require access to Kala Pharmaceuticals' financial statements and up-to-date market data. To gain more insights about the company, read Mission Statement, Vision, & Core Values of Kala Pharmaceuticals, Inc. (KALA).

Kala Pharmaceuticals, Inc. (KALA) Market Position & Future Outlook

Kala Pharmaceuticals is navigating a challenging market landscape, focusing on innovative therapies for eye diseases while facing significant competition and financial hurdles. Their future success hinges on strategic execution and capitalizing on market opportunities.

Competitive Landscape

Company Market Share, % Key Advantage
Kala Pharmaceuticals, Inc. Approx. 1-2% (niche market segments) Novel mucus-penetrating particle (MPP) technology for targeted drug delivery to the eye.
Novartis Approx. 20-25% (ophthalmology market) Extensive portfolio of established ophthalmic products and strong global presence.
Allergan (AbbVie) Approx. 15-20% (ophthalmology market) Leading brand recognition and a wide range of products, including treatments for dry eye disease and glaucoma.

Opportunities & Challenges

Opportunities Risks
Potential FDA approval and successful commercialization of new pipeline products, particularly those utilizing the MPP technology. Intense competition from larger pharmaceutical companies with greater resources and established market presence.
Strategic partnerships or collaborations to expand market reach and access new technologies. Regulatory hurdles and potential delays in the approval process for new drugs.
Growing prevalence of eye diseases, creating increased demand for effective treatments. Financial constraints and the need to secure additional funding to support research and development and commercialization efforts.

Industry Position

Kala Pharmaceuticals holds a niche position within the broader ophthalmology market, characterized by:

  • Focus on innovative drug delivery using its proprietary MPP technology.
  • Targeting specific unmet needs in eye care, such as dry eye disease and post-operative inflammation.
  • Facing significant competition from larger, more established players with greater market share and resources.

To learn more about the company's mission, vision and core values, visit: Mission Statement, Vision, & Core Values of Kala Pharmaceuticals, Inc. (KALA).

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