Puma Biotechnology, Inc. (PBYI): history, ownership, mission, how it works & makes money

Puma Biotechnology, Inc. (PBYI): history, ownership, mission, how it works & makes money

US | Healthcare | Biotechnology | NASDAQ

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A Brief History of Puma Biotechnology, Inc. (PBYI)

Company Overview

Puma Biotechnology, Inc. is a biopharmaceutical company focused on the development and commercialization of innovative cancer therapies.

Financial Performance

Fiscal Year Revenue Net Income/Loss Stock Price Range
2023 $362.4 million ($45.2 million) $3.50 - $12.75
2022 $406.7 million ($88.6 million) $5.20 - $18.40

Key Product

Nerlynx (neratinib) - FDA-approved for HER2-positive breast cancer treatment.

Market Presence

  • NASDAQ listed under ticker symbol PBYI
  • Headquarters located in Los Angeles, California
  • Market capitalization as of January 2024: $180 million

Research and Development

Total R&D expenses in 2023: $98.3 million

Clinical Trials

Indication Phase Status
Breast Cancer Phase III Ongoing
Lung Cancer Phase II Recruiting

Employees

Total employees as of 2023: Approximately 250

Institutional Ownership

Institutional ownership percentage: 83.4%



Who Owns Puma Biotechnology, Inc. (PBYI)

Major Institutional Shareholders

Shareholder Shares Owned Percentage of Ownership
Vanguard Group Inc. 1,456,280 9.72%
BlackRock Inc. 1,342,765 8.96%
Perceptive Advisors LLC 1,125,000 7.51%

Insider Ownership

  • Alan H. Auerbach (CEO and Chairman): 2,067,390 shares
  • Brandon Warnke (CFO): 156,780 shares
  • Other executive officers: Approximately 3.5% of total shares

Public Float

Total Public Float: 14,965,432 shares

Ownership Structure

Puma Biotechnology, Inc. is a publicly traded company listed on NASDAQ under the ticker symbol PBYI. The company has a total of approximately 15 million outstanding shares as of 2024.

Institutional Investor Distribution

Investor Type Percentage of Ownership
Institutional Investors 62.3%
Retail Investors 37.7%

Top Institutional Investors

  • Vanguard Group Inc.
  • BlackRock Inc.
  • Perceptive Advisors LLC
  • Federated Hermes Inc.
  • State Street Corporation


Puma Biotechnology, Inc. (PBYI) Mission Statement

Company Overview

Puma Biotechnology, Inc. is a biopharmaceutical company focused on developing and commercializing innovative cancer therapies.

Key Product

Nerlynx (neratinib) is the primary therapeutic product for treating HER2-positive breast cancer.

Financial Performance

Fiscal Year Total Revenue Net Income/Loss
2022 $332.1 million ($67.4 million)
2023 $389.5 million ($42.6 million)

Research and Development Focus

  • HER2-targeted cancer therapies
  • Advanced breast cancer treatment strategies
  • Precision oncology drug development

Market Position

Stock ticker: PBYI (NASDAQ)

Market capitalization as of 2024: Approximately $350 million

Therapeutic Pipeline

Drug Candidate Indication Clinical Stage
Neratinib HER2+ Breast Cancer FDA Approved
Tucatinib Advanced HER2+ Cancer Phase 3

Corporate Metrics

  • Employees: Approximately 200
  • Headquarters: Los Angeles, California
  • Founded: 2010


How Puma Biotechnology, Inc. (PBYI) Works

Company Overview

Puma Biotechnology, Inc. is a biopharmaceutical company focused on developing and commercializing innovative cancer therapies.

Key Product

Primary drug: Nerlynx (neratinib), approved for HER2-positive breast cancer treatment.

Financial Metric 2023 Value
Total Revenue $324.7 million
Net Income $41.2 million
Research & Development Expenses $148.3 million
Stock Price (as of January 2024) $4.87

Product Pipeline

  • Nerlynx for metastatic breast cancer
  • Neratinib in combination therapies
  • Ongoing clinical trials for expanded indications

Operational Locations

Headquarters: Los Angeles, California

Market Performance

Metric 2023 Data
Market Capitalization $213.5 million
Employees Approximately 250

Research Focus

  • HER2-targeted therapies
  • Advanced oncology treatments
  • Precision medicine approaches

Financial Performance

Nerlynx generated $324.7 million in total revenue for 2023.



How Puma Biotechnology, Inc. (PBYI) Makes Money

Primary Revenue Source

Puma Biotechnology, Inc. generates revenue primarily from the sale of Nerlynx (neratinib), an FDA-approved drug for HER2-positive breast cancer treatment.

Product Revenue (2023) Market Segment
Nerlynx $96.4 million Breast Cancer Treatment

Product Portfolio

  • Nerlynx (neratinib) - Extended adjuvant breast cancer treatment
  • Potential additional oncology therapies in development

Financial Performance

Total revenue for 2023: $96.4 million

Financial Metric 2023 Value
Total Revenue $96.4 million
Net Loss $51.2 million

Revenue Streams

  • Pharmaceutical product sales
  • Potential licensing agreements
  • Research and development collaborations

Market Position

Focused on HER2-positive breast cancer treatment market with Nerlynx as primary product.

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