Surrozen, Inc. (SRZN): History, Ownership, Mission, How It Works & Makes Money

Ever wondered about the science behind tissue regeneration and how it could revolutionize medicine? Surrozen, Inc. (SRZN) is a preclinical stage biopharmaceutical company focused on discovering and developing novel regenerative medicines with a history of losses. But how exactly does Surrozen aim to turn preclinical promise into tangible treatments, and what's their strategy for long-term success? Keep reading to explore Surrozen's history, ownership, mission, technology, and revenue model.

Surrozen, Inc. (SRZN) History

Founding Timeline

Year established

The company was established in 2016.

Original location

The company was originally located in South San Francisco, California.

Founding team members

The founding team included:

• K. Christopher Garcia, PhD
• Calvin Kuo, MD, PhD
• Roel Nusse, PhD

Initial capital/funding

In 2016, the company obtained $50 million in Series A funding led by The Column Group.

Evolution Milestones

Transformative Moments

• Focus on Wnt Signaling: A key transformative decision was the company's focus on leveraging Wnt signaling pathways for tissue regeneration. This focus shaped their research and development efforts.
• Clinical Development: Transitioning from preclinical research to clinical trials marked a significant step. The initiation of Phase 1 trials for SRZ-259 was a pivotal moment.
• Public Listing via Merger: The merger with Consummation Business Combination Corp. and subsequent public listing provided substantial capital. This allowed the company to advance its programs more aggressively.
• Pipeline Expansion: Expanding the pipeline to include programs like SRZ-452 for retinal disorders demonstrated a strategic shift towards addressing multiple therapeutic areas with Wnt-based regenerative medicines.

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Surrozen, Inc. (SRZN) Ownership Structure

Understanding a company's ownership structure provides insights into its control and governance, revealing who has the power to influence its decisions and direction. The ownership structure of **Surrozen, Inc.** involves a mix of institutional and individual shareholders.

Surrozen, Inc.'s Current Status

**Surrozen, Inc.** is a public company, trading under the ticker symbol **SRZN**. This means that its shares are available for purchase by the general public on a stock exchange.

Surrozen, Inc.'s Ownership Breakdown

Information regarding the exact ownership breakdown of **Surrozen, Inc.** can fluctuate and is typically detailed in the company's filings with the Securities and Exchange Commission (**SEC**). These filings, such as the **13F** filings, disclose the holdings of institutional investors. However, the latest data reveals the following general ownership structure:

Surrozen, Inc.'s Leadership

The leadership team is crucial for guiding the strategy and operations of **Surrozen, Inc.** As of April 2025, key members include:

• Nassib Chamoun serves as Chief Executive Officer
• Jamesльтило holds the position of Chief Medical Officer
• Stephen Tanda is the Chief Business Officer of the company

These individuals, along with other members of the executive team, are responsible for the day-to-day management and strategic direction of **Surrozen, Inc.**

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Surrozen, Inc. (SRZN) Mission and Values

Surrozen, Inc. is dedicated to discovering, developing, and commercializing novel regenerative medicines to address significant unmet medical needs. The company's mission is rooted in pioneering targeted therapeutics that harness the body's innate ability to repair and regenerate tissues.

Surrozen's Core Purpose

Official mission statement

While a direct, concise mission statement for Surrozen, Inc. isn't explicitly available in recent search results, their work and focus indicate a mission centered around:

• Developing regenerative medicines to repair damaged tissues and organs.
• Pioneering innovative therapies that leverage the body's natural regenerative capabilities.
• Addressing unmet medical needs in areas with limited or no effective treatment options.

Vision statement

Based on Surrozen's focus and activities, their vision can be inferred as:

• To be a leader in the field of regenerative medicine, transforming the treatment of diseases and injuries.
• To create a future where damaged tissues and organs can be effectively repaired, restoring health and improving quality of life.
• To establish regenerative medicine as a mainstream therapeutic approach, accessible to patients worldwide.

Company slogan/tagline

As of the last update, Surrozen, Inc. does not have a widely publicized official slogan or tagline. However, reflecting their work, a potential tagline could be:

• 'Regenerating the Future of Medicine.'
• 'Unlocking the Body's Healing Power.'
• 'Targeted Regeneration for a Healthier Tomorrow.'

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Surrozen, Inc. (SRZN) How It Works

Surrozen, Inc. is a biotechnology company focused on discovering and developing novel regenerative medicines to address diseases with significant unmet medical needs. The company's approach centers on harnessing the body's innate ability to repair and regenerate tissues through targeted activation of the Wnt signaling pathway.

Surrozen's Product/Service Portfolio

Surrozen's Operational Framework

Surrozen's operations are built around a research and development engine focused on Wnt signaling. Key aspects of their operational framework include:

• Target Identification and Validation: Identifying specific Wnt ligands and receptors that play critical roles in tissue regeneration for particular diseases.
• Antibody Development: Creating proprietary antibodies that selectively activate these Wnt pathways to promote tissue repair and regeneration.
• Preclinical Studies: Conducting rigorous preclinical testing to evaluate the safety and efficacy of their therapeutic candidates in relevant disease models.
• Clinical Trials: Advancing promising candidates into clinical trials to assess their potential to treat human diseases. For instance, SZN-043 initiated Phase 1 clinical trials in the first half of 2023.
• Manufacturing and Supply Chain: Establishing robust manufacturing processes and supply chains to support clinical development and potential commercialization.

Surrozen's Strategic Advantages

Surrozen's strategic advantages stem from its innovative approach to regenerative medicine and its expertise in Wnt signaling:

• Novel Therapeutic Approach: Surrozen's focus on activating the Wnt pathway for tissue regeneration represents a unique approach with the potential to address the underlying causes of many diseases.
• Proprietary Technology: The company has developed a proprietary platform for discovering and developing Wnt-activating antibodies, providing a competitive edge.
• Experienced Team: Surrozen's management team and scientific advisors bring extensive experience in regenerative medicine, antibody development, and clinical development.
• Strategic Partnerships: Collaborations with leading academic institutions and other companies can provide access to additional expertise, technologies, and resources.

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Surrozen, Inc. (SRZN) How It Makes Money

Surrozen, Inc., prior to its merger with Twin Ridge Capital Acquisition Corp. and subsequent name change to REGENXBIO Inc. (RGNX), focused on developing regenerative medicines. Revenue generation was primarily anticipated through potential future licensing agreements and eventual sales of its therapeutic products, which were in the preclinical development stage.

REGENXBIO Inc. (RGNX) Revenue Breakdown

As Surrozen is now part of REGENXBIO Inc., it's more relevant to examine REGENXBIO's revenue streams. REGENXBIO generates revenue primarily through licensing fees, royalties, and research and development collaborations.

REGENXBIO Inc. (RGNX) Business Economics

REGENXBIO's business economics are rooted in the high-risk, high-reward nature of biotechnology. Key aspects include:

• High R&D Investment: Significant capital is allocated to research and development, reflecting the long lead times and regulatory hurdles inherent in bringing novel therapies to market.
• Intellectual Property: Patents and proprietary technology are critical assets, providing market exclusivity and protecting their innovations.
• Strategic Collaborations: Partnerships with larger pharmaceutical companies can provide funding, expertise, and resources for clinical development and commercialization.
• Regulatory Milestones: Achieving key regulatory milestones, such as FDA approval, is crucial for unlocking substantial revenue streams.

REGENXBIO Inc. (RGNX) Financial Performance

To gauge REGENXBIO's financial performance, consider the following points:

• Revenue Growth: Track the growth in licensing fees, royalties, and collaboration revenue, as these indicate the increasing value and market acceptance of their gene therapy platforms.
• R&D Expenditure: Monitor R&D expenses as a percentage of revenue to assess the company's commitment to innovation and future growth.
• Cash Position: Evaluate the company's cash reserves and runway, as this indicates their ability to fund ongoing operations and clinical trials.
• Net Income/Loss: Analyze net income or loss to understand overall profitability, keeping in mind that many biotech companies operate at a loss during development stages.

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Surrozen, Inc. (SRZN) Market Position & Future Outlook

Surrozen is navigating a challenging market landscape, aiming to establish itself as a leader in regenerative medicine. Success hinges on clinical trial outcomes and strategic partnerships.

Competitive Landscape

The regenerative medicine sector is characterized by intense competition and rapid innovation. Defining precise market share is challenging due to the diverse range of therapies and ongoing clinical developments. However, we can identify key players and their competitive advantages:

Opportunities & Challenges

Surrozen faces both significant opportunities and potential risks as it moves forward.

Industry Position

Surrozen's position within the regenerative medicine industry can be characterized by the following:

• Innovative Technology: Surrozen is focused on leveraging its proprietary technology to address unmet needs in tissue regeneration.
• Early Stage: As a relatively young company, Surrozen is still in the early stages of clinical development and commercialization.
• High-Risk, High-Reward: The company's success is heavily dependent on the outcome of its clinical trials, making it a high-risk, high-reward investment.

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