Exploring Synlogic, Inc. (SYBX) Investor Profile: Who’s Buying and Why?

Have you ever wondered who the major players are behind Synlogic, Inc. (SYBX), and what their investment decisions might signal? As of April 2025, digging into the ownership structure of Synlogic reveals a mix of institutional, insider, and retail investors, each holding significant stakes. Institutional investors hold approximately 64.60% of the company, while insiders account for about 11.79%. Are these institutional giants accumulating more shares, or are insiders selling off their stakes? With the share price at $1.01 as of April 11, 2025, a 43.89% decline from $1.80 on April 15, 2024, understanding who is investing and why becomes crucial for gauging the company's future prospects. Let's delve into the details of Synlogic's investor profile to uncover the motivations driving these investment decisions.

Synlogic, Inc. (SYBX) Who Invests in Synlogic, Inc. (SYBX) and Why?

Understanding the investor profile of Synlogic, Inc. (SYBX) provides insights into the market's perception of the company and its future prospects. Synlogic, a biopharmaceutical company focused on developing Synthetic Biotic medicines, attracts a diverse range of investors with varying motivations and strategies. Here's a breakdown of the key investor types, their investment motivations, and typical strategies.

Synlogic's investor base can be broadly categorized into the following:

• Institutional Investors: These include investment companies, hedge funds, pension funds, and other financial institutions.
• Retail Investors: Individual investors who buy and sell shares for their own accounts.
• Insiders: Company executives and board members who own shares of the company.

According to recent data, Synlogic's ownership structure comprises:

• Institutional Investors: Approximately 62.3% of shares.
• Insider Ownership: Around 5.8%.
• Retail Investors: Approximately 31.9%.

Let's delve deeper into each category:

Institutional Investors

As of early April 2025, Synlogic has 33 institutional owners and shareholders that have filed 13D/G or 13F forms with the Securities Exchange Commission (SEC), holding a total of 6,847,849 shares.

Major Institutional Shareholders:

• Cable Car Capital LLC
• NEA Management Company, LLC
• Vanguard Group Inc
• Fmr Llc
• VTSMX - Vanguard Total Stock Market Index Fund Investor Shares
• QVG2Q - Growth Portfolio Investor Class
• Geode Capital Management, Llc
• EPGAX - Fidelity Advisor Equity Growth Fund Class A
• VEXMX - Vanguard Extended Market Index Fund Investor Shares
• FSMAX - Fidelity Extended Market Index Fund

These institutions vary in their investment philosophies and strategies, but their collective presence indicates a significant level of interest in Synlogic's potential.

Investment Motivations:

Institutional investors are often attracted to Synlogic due to several factors:

• Growth Prospects: Synlogic's focus on Synthetic Biotic medicines and its pipeline of drug candidates targeting rare metabolic and immunological diseases present significant growth opportunities.
• Innovation: The company's proprietary Synthetic Biotic platform and its approach to engineering living bacterial therapies are seen as innovative and potentially transformative.
• Market Position: Synlogic's focus on rare diseases, where there are often limited treatment options, gives it a unique market position.

Investment Strategies:

The investment strategies employed by institutional investors in Synlogic can vary:

• Long-Term Holding: Some institutions may adopt a long-term holding strategy, investing in Synlogic with the expectation of long-term growth and value creation.
• Short-Term Trading: Other institutions may engage in short-term trading, seeking to profit from short-term price fluctuations.
• Value Investing: Some investors may see Synlogic as undervalued and invest with the expectation that the market will eventually recognize its true value.

Retail Investors

Retail investors comprise a notable portion of Synlogic's shareholder base. These investors may be drawn to Synlogic for various reasons, including:

• Potential for High Returns: The biotechnology sector can offer the potential for high returns, and retail investors may be attracted to Synlogic's innovative approach and pipeline of drug candidates.
• Socially Responsible Investing: Some retail investors may be interested in Synlogic's focus on developing treatments for rare diseases, aligning with socially responsible investing principles.
• Speculative Trading: Some retail investors may engage in speculative trading, seeking to profit from short-term price movements based on news and developments related to the company.

Insiders

Insider ownership is another important aspect of Synlogic's investor profile. Significant insider ownership can indicate that the company's management and board members have confidence in its future prospects.

Top Insider Ownership:

• Todd Zion (Co-Founder): 425,000 shares
• Kevin Havenga (CEO): 298,675 shares
• Matthew Shair (Board Member): 175,432 shares

It's worth noting that M. James Barrett is identified as the largest individual shareholder, owning 8,047,880 shares, representing 68.81% of the company, with an approximate value of $9.98 million as of April 2025.

Recent Developments and Strategic Shifts

Recent events have significantly impacted Synlogic's strategic direction and, consequently, investor sentiment. In February 2024, Synlogic announced the discontinuation of its Synpheny-3 study for PKU and initiated a review of strategic options to enhance shareholder value. This led to a workforce reduction of over 90% and the departure of the CEO.

In response to unsolicited accumulation of shares, Synlogic implemented a shareholder rights plan, effective from February 20, 2024, to February 20, 2025. This plan aimed to prevent unwanted takeover attempts and ensure fair value for all shareholders.

Financial Performance and Analyst Sentiment

Synlogic's financial performance in 2024 showed revenue of only $8,000, a significant decrease from $3.37 million the previous year. Losses amounted to -$23.36 million, an improvement compared to 2023. As of March 2025, Synlogic had a market capitalization of $14.0 million.

It's important to note that analyst ratings and price targets for Synlogic may be limited or unavailable, reflecting the company's current strategic uncertainties.

For further insights into Synlogic's mission, vision, and core values, you can explore: Mission Statement, Vision, & Core Values of Synlogic, Inc. (SYBX).

Disclaimer: Investment decisions should be based on thorough research and consultation with a financial advisor, considering individual circumstances and risk tolerance. The data provided here is for informational purposes and should not be considered financial advice.

Synlogic, Inc. (SYBX) Institutional Ownership and Major Shareholders of Synlogic, Inc. (SYBX)

Institutional ownership in Synlogic, Inc. (SYBX) reflects the extent to which major financial institutions, hedge funds, and other entities hold the company's shares. Analyzing this ownership structure can provide insights into market sentiment and potential stock performance. As of recent filings, Synlogic, Inc. has a notable presence of institutional investors.

According to recent data, 33 institutional owners and shareholders have filed 13D/G or 13F forms with the Securities Exchange Commission (SEC), holding a total of 6,847,849 shares. These major shareholders include:

• Cable Car Capital LLC
• NEA Management Company, LLC
• Vanguard Group Inc
• Fmr Llc
• VTSMX - Vanguard Total Stock Market Index Fund Investor Shares
• QVG2Q - Growth Portfolio Investor Class
• Geode Capital Management, Llc
• EPGAX - Fidelity Advisor Equity Growth Fund Class A
• VEXMX - Vanguard Extended Market Index Fund Investor Shares
• FSMAX - Fidelity Extended Market Index Fund

These institutions play a significant role in Synlogic's stock dynamics.

Examining the percentage of shares held by different investor types offers a clearer picture of Synlogic's ownership composition. Recent data indicates:

• 64.60% of shares are held by institutions
• 11.79% of shares are held by insiders

The institutional ownership structure of Synlogic, Inc. (NasdaqCM: SYBX) reveals current positions held by institutions and funds, along with the latest changes in their holdings. Major shareholders can be individual investors, mutual funds, hedge funds, or institutions. It's worth noting that Schedule 13D filings indicate investors holding (or having held) over 5% of the company's shares, potentially aiming to influence business strategies. Meanwhile, Schedule 13G filings suggest passive investments exceeding 5%.

To gain more insight into Synlogic's mission, vision, and core values, visit: Mission Statement, Vision, & Core Values of Synlogic, Inc. (SYBX).

Changes in institutional ownership can significantly influence a company's stock price. Increases in institutional holdings often signal confidence in the company's future prospects, potentially driving up the stock price. Conversely, decreases may indicate concerns, leading to a price decline. Monitoring these changes provides valuable insights.

The fund sentiment score, also known as the Ownership Accumulation Score, identifies stocks that are heavily bought by funds. It uses a quantitative model considering the increase in disclosed owners, changes in portfolio allocations, and other metrics. The score ranges from 0 to 100, with higher numbers indicating greater accumulation compared to peers; 50 is the average.

While specific data on recent increases or decreases in institutional stakes is not available, keeping an eye on 13F filings and other ownership disclosures is crucial for staying informed about shifts in institutional sentiment. These filings provide a detailed view of who is buying and selling Synlogic shares, offering clues about the potential direction of the stock.

Institutional investors can exert considerable influence on Synlogic’s stock price and strategic direction. Their actions often reflect in the company's stock price, and their insights can shape company strategy through active engagement and voting rights. Here's how they make an impact:

• Stock Price Volatility: Large trades by institutions can lead to significant short-term price swings.
• Long-Term Stability: Sustained institutional support can provide stability and investor confidence.
• Strategic Influence: Major shareholders may engage with management, influencing decisions on mergers, acquisitions, and overall corporate strategy.

Synlogic's stock has experienced volatility. As of April 11, 2025, the share price was $1.01. On April 15, 2024, it was $1.80, representing a 43.89% decline.

In February 2024, Synlogic implemented a shareholder rights plan, effective for one year, in response to unsolicited accumulation of shares by an unidentified investor. Each stockholder received one right per share, exercisable if a person or group acquires 15% (or 20% for passive institutional investors) of outstanding common stock without board approval, potentially purchasing shares at double the price. The Board also engaged Ladenburg Thalmann & Co. Inc. to explore strategic alternatives.

Understanding the roles and actions of these major players is essential for anyone investing in Synlogic, Inc.

Synlogic, Inc. (SYBX) Key Investors and Their Impact on [Company Name]

Understanding the investor profile of Synlogic, Inc. (SYBX) provides valuable insights into the company's stability, growth potential, and strategic direction. Institutional investors, individual shareholders, and recent investment moves can all influence Synlogic's stock performance and corporate decisions.

As of April 2025, several institutions and individuals have significant holdings in Synlogic, Inc. (SYBX). According to recent filings with the Securities and Exchange Commission (SEC), 33 institutional owners and shareholders hold a total of 6,847,849 shares.

Here's a breakdown of some notable investors:

• Cable Car Capital LLC: A significant shareholder.
• NEA Management Company, LLC: Another major institutional investor.
• Vanguard Group Inc: Holds 1,256,374 shares, representing 8.72% ownership.
• Fmr Llc: Also among the top shareholders.
• Blackrock Inc: Holds 1,042,567 shares, accounting for 7.24% of ownership.
• Geode Capital Management LLC: Holds 512,983 shares, which is 3.56% ownership.

Other institutional investors include VTSMX - Vanguard Total Stock Market Index Fund Investor Shares, QVG2Q - Growth Portfolio Investor Class, Geode Capital Management, Llc, EPGAX - Fidelity Advisor Equity Growth Fund Class A, VEXMX - Vanguard Extended Market Index Fund Investor Shares, and FSMAX - Fidelity Extended Market Index Fund.

Top insider ownership includes:

• Todd Zion (Co-Founder): Holds 425,000 shares.
• Kevin Havenga (CEO): Holds 298,675 shares.
• Matthew Shair (Board Member): Holds 175,432 shares.

The ownership structure of Synlogic, Inc. (SYBX) is as follows:

• Institutional Investors: 62.3%
• Insider Ownership: 5.8%
• Retail Investors: 31.9%

The influence of these investors can be seen in various aspects of Synlogic's operations. Large institutional investors often have the resources to conduct thorough due diligence and can significantly impact a company's stock price based on their investment decisions. Their involvement can also provide stability and confidence to the market.

Recent moves by investors can signal important changes in sentiment and expectations. For example, a Schedule 13D filing indicates that an investor holds (or held) more than 5% of the company and intends (or intended) to actively pursue a change in business strategy. A Schedule 13G filing indicates a passive investment of over 5%.

Some recent activities of activist investors include:

• Kryzanowski John A: Decreased shares from 873,722 to 733,412, a -16.06% change, with ownership decreasing by -34.07%.
• ARMISTICE CAPITAL, LLC: Reduced shares from 1,285,542 to 614,288, a -52.22% change, with ownership decreasing by -50.05%.
• New Enterprise Associates 14, L.P.: Held steady at 2,922,774 shares, representing 25.00% ownership, a -27.33% change.

These changes in ownership may reflect shifts in investor confidence or strategic realignments within these investment firms.

To protect stockholders from unsolicited accumulation of shares, Synlogic's Board of Directors approved a limited duration shareholder rights plan, effective from February 20, 2024, expiring on February 20, 2025. This plan was adopted following an unsolicited accumulation of shares by a certain investor and is intended to ensure that all stockholders realize the long-term value of their investment.

The company also engaged Ladenburg Thalmann & Co. Inc. as its financial advisor to assist in a review and evaluation of strategic options, aiming to maximize shareholder value.

Here's a brief overview of Synlogic's financial data:

As of March 25, 2025, the share price of Synlogic, Inc. was $1.30 / share, and its market cap as of March 24, 2025, was $15.20 MM.

For more insights into Synlogic, Inc.'s background, mission, and operations, you can visit: Synlogic, Inc. (SYBX): History, Ownership, Mission, How It Works & Makes Money

Synlogic, Inc. (SYBX) Market Impact and Investor Sentiment

Understanding investor sentiment and market reactions to Synlogic, Inc. (SYBX) is crucial for assessing the company's current standing and future potential. Analyzing these factors provides insights into how major shareholders perceive the company and how the stock market responds to significant ownership changes or investor activities.

While pinpointing the exact current sentiment of major shareholders as of today can be challenging without direct statements or filings, observing recent market behaviors and analyst ratings can offer clues. Generally, positive sentiment from major shareholders often correlates with increased investment, stability in stock prices, and favorable long-term outlooks. Conversely, negative sentiment might lead to decreased holdings, stock volatility, and potential downturns.

Recent market reactions to Synlogic, Inc. (SYBX) can be evaluated by examining stock performance following key announcements related to ownership or significant investor moves. For instance, a substantial purchase by a well-known institutional investor might drive the stock price up, reflecting increased confidence in the company's prospects. Conversely, a large sell-off could lead to a price decline, signaling concern among investors.

Analyst perspectives play a vital role in interpreting the impact of key investors on Synlogic, Inc. (SYBX)'s future. Analysts often provide ratings (e.g., buy, hold, sell) and price targets based on their assessment of the company's financial health, pipeline progress, and market conditions. These insights can help investors understand the potential implications of major investor decisions. For example, if analysts upgrade their rating following a strategic investment, it suggests that the investor's move is seen as a positive catalyst for the company's growth.

To gain a deeper understanding of Synlogic, Inc. (SYBX), consider exploring this resource: Synlogic, Inc. (SYBX): History, Ownership, Mission, How It Works & Makes Money

Monitoring ownership trends and institutional holdings can provide valuable context. Major institutional investors' decisions often reflect their comprehensive analysis and long-term investment strategies.

Key aspects to consider regarding investor sentiment and market reactions include:

• Institutional Ownership: Tracking the percentage of shares held by institutions.
• Major Transactions: Identifying significant purchases or sales by key investors.
• Analyst Ratings: Following changes in analyst ratings and price targets.
• Market Performance: Observing stock price movements in response to investor news.

For example, examining the most recent data on institutional ownership can reveal whether these entities are increasing or decreasing their positions in Synlogic, Inc. (SYBX). Significant changes in institutional holdings often precede notable shifts in stock performance. Keeping tabs on these activities helps in gauging the overall market confidence in the company.

While exact real-time sentiment is elusive, these indicators collectively provide a nuanced view of how the market and major investors perceive Synlogic, Inc. (SYBX).