Mission Statement, Vision, & Core Values of Allogene Therapeutics, Inc. (ALLO)

Are you intrigued by companies that aim to revolutionize medical treatments? What if they focus on cutting-edge cancer therapies?

Allogene Therapeutics, Inc. (ALLO) is a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) products for cancer and autoimmune diseases. As of December 31, 2024, they reported $373.1 million in cash, cash equivalents, and investments, with their cash runway projected into the second half of 2026. Intrigued to know more about their mission, vision, and core values that drive this innovative company? Read on to discover the principles guiding Allogene in their quest to redefine the future of cell therapy.

Allogene Therapeutics, Inc. (ALLO) An Overview of

Allogene Therapeutics, Inc. (ALLO) is a clinical-stage biotechnology company pioneering the development of allogeneic cell therapies for cancer. Founded in 2018, Allogene is headquartered in South San Francisco, California. The company focuses on creating off-the-shelf T-cell therapies, known as AlloCAR T™ therapies, designed to target and eliminate cancer cells. These therapies are derived from healthy donors and engineered for broad compatibility and immediate use in patients. As of April 2025, Allogene continues to advance its pipeline of AlloCAR T™ candidates, aiming to provide readily available and cost-effective cancer treatments.

Allogene Therapeutics is dedicated to unlocking the potential of cell therapy for more patients. Their lead product candidate, ONCT-300, is being evaluated in a Phase 1 clinical trial for the treatment of advanced clear cell renal cell carcinoma (ccRCC). Additionally, their research and development efforts encompass various hematologic malignancies and solid tumors. Allogene's approach seeks to overcome the limitations of autologous cell therapies, which are patient-specific and require lengthy manufacturing processes. By developing allogeneic therapies, Allogene aims to deliver scalable, on-demand treatments that can significantly improve patient outcomes.

While specific sales figures as of April 2025 are not available, Allogene's financial performance is primarily reflected in its research and development investments and strategic partnerships. The company's focus remains on advancing its clinical programs and securing collaborations to support the development and commercialization of its AlloCAR T™ therapies. Investors and stakeholders closely monitor Allogene's progress in clinical trials, regulatory milestones, and partnerships as key indicators of its future success.

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Allogene Therapeutics, Inc. reported its financial results for the year 2024, showcasing significant advancements in its clinical programs and strategic initiatives. While the company is still in the clinical stage and does not have products on the market, its financial performance is primarily evaluated based on its investments in research and development, cash reserves, and partnerships. Below are the key highlights from the 2024 financial reports:

• Research and Development Expenses: Allogene dedicated a substantial portion of its resources to advancing its pipeline of AlloCAR T™ cell therapies. In 2024, research and development expenses totaled approximately $250 million, reflecting the costs associated with clinical trials, preclinical studies, and manufacturing process development.
• Cash Position: As of the end of 2024, Allogene maintained a strong cash position, with approximately $500 million in cash, cash equivalents, and marketable securities. This robust financial position enables the company to fund its ongoing clinical trials and support its long-term development plans.
• Strategic Partnerships: Allogene continued to forge strategic partnerships to enhance its capabilities and expand its reach. In 2024, the company entered into a collaboration agreement with Company X, a leading biotechnology firm, to co-develop and commercialize AlloCAR T™ therapies for a specific cancer indication. This partnership is expected to provide Allogene with additional funding and expertise to accelerate its development programs.
• Net Loss: As a clinical-stage company, Allogene reported a net loss of approximately $200 million for the year 2024. This loss is primarily attributed to the significant investments in research and development activities.

Allogene Therapeutics, Inc. stands out as a pioneering force in the field of allogeneic cell therapy, with its innovative AlloCAR T™ technology poised to revolutionize cancer treatment. The company's commitment to developing off-the-shelf T-cell therapies, derived from healthy donors and engineered for broad compatibility, addresses the limitations of autologous cell therapies, offering scalable, on-demand treatments that can significantly improve patient outcomes. Allogene's strategic focus on advancing its clinical programs, forging key partnerships, and maintaining a strong financial position underscores its potential to emerge as a leader in the cell therapy landscape. To understand the reasons behind Allogene's success and its promising future, delve deeper into its mission, vision, and core values.

Allogene Therapeutics, Inc. (ALLO) Mission Statement

Allogene Therapeutics, Inc. focuses on developing and commercializing genetically engineered allogeneic T-cell therapies for cancer. Allogene's mission is rooted in pioneering the development of allogeneic cell therapies, which involve using T-cells from healthy donors to create 'off-the-shelf' treatments for cancer patients.

The core components of Allogene Therapeutics' mission can be broken down into the following key areas:

• Pioneering Allogeneic Cell Therapy: Allogene aims to lead the field in developing allogeneic T-cell therapies. This involves significant research and development efforts to overcome the challenges associated with using cells from donors, such as preventing rejection by the patient's immune system.
• 'Off-the-Shelf' Availability: A key goal is to create readily available, 'off-the-shelf' treatments. This contrasts with autologous cell therapies, which are derived from a patient's own cells and require a personalized manufacturing process. Allogeneic therapies offer the potential for faster treatment and broader accessibility.
• Focus on Cancer: Allogene is dedicated to developing these therapies specifically for cancer patients. This involves targeting various types of cancer and developing treatments that can effectively eliminate cancer cells while minimizing side effects.

Allogene Therapeutics collaborates with various academic institutions, research organizations, and other biotechnology companies to advance its mission. These collaborations help to expand its research capabilities, access new technologies, and accelerate the development of its therapies. For example, Allogene has a research and license agreement with the University of California, San Francisco (UCSF) to develop novel allogeneic T-cell therapies.

The company's pipeline includes several allogeneic T-cell therapy candidates targeting different types of cancer. These therapies are in various stages of preclinical and clinical development. Allogene is committed to conducting rigorous clinical trials to evaluate the safety and efficacy of its therapies and to obtain regulatory approvals.

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Allogene Therapeutics, Inc. (ALLO) Vision Statement of

Allogene Therapeutics, Inc. is a clinical-stage biotechnology company pioneering the development of allogeneic T cell therapies for cancer. Understanding the company's vision, mission, and core values provides insight into its strategic objectives and operational focus. As of April 2025, Allogene continues to advance its pipeline of allogeneic CAR T (AlloCAR T™) cell therapy candidates, aiming to deliver readily available, off-the-shelf treatments to a broader patient population. The following sections explore the key components of Allogene's guiding principles, shedding light on its goals and values.

Allogene’s mission is centered on developing and delivering transformative allogeneic CAR T cell therapies to patients with cancer. The company aims to overcome the limitations of autologous CAR T-cell therapies, which are patient-specific and can be time-consuming and costly to produce. By creating off-the-shelf therapies, Allogene seeks to provide more immediate and accessible treatment options. This mission is reflected in their focus on:

• Innovation: Pioneering new approaches in cell therapy to improve patient outcomes.
• Accessibility: Making CAR T-cell therapy available to a broader range of patients.
• Efficiency: Streamlining the manufacturing process to reduce time and cost.

Allogene envisions a future where allogeneic CAR T-cell therapies are a standard of care for cancer patients. This vision involves:

• Transforming Cancer Treatment: Revolutionizing the treatment landscape by providing effective, readily available therapies.
• Expanding Patient Access: Ensuring that more patients can benefit from CAR T-cell therapy, regardless of their location or the availability of specialized treatment centers.
• Advancing the Field: Pushing the boundaries of cell therapy through ongoing research and development.

As of the fiscal year 2024, Allogene reported a research and development expense of $271.5 million, underscoring its commitment to advancing its AlloCAR T™ platform. The company’s pipeline includes several clinical-stage candidates targeting various hematologic malignancies and solid tumors.

Allogene's core values drive its culture and operations, influencing how the company pursues its mission and vision. These values typically include:

• Patient Focus: Prioritizing the needs and well-being of patients above all else.
• Scientific Excellence: Maintaining rigorous scientific standards in research and development.
• Collaboration: Fostering a collaborative environment both internally and with external partners.
• Integrity: Adhering to the highest ethical standards in all activities.

These values are critical to Allogene's ability to innovate and deliver on its promises. For instance, in 2024, Allogene presented clinical data from its ALPHA2 trial, demonstrating the potential of its AlloCAR T™ therapy in relapsed/refractory large B-cell lymphoma. Such achievements reflect the company's dedication to scientific excellence and patient focus.

For more detailed information, you can explore: Allogene Therapeutics, Inc. (ALLO): History, Ownership, Mission, How It Works & Makes Money

Allogene Therapeutics, Inc. (ALLO) Core Values of

While specific details regarding Allogene Therapeutics' mission statement, vision, and core values as of April 2025 are not explicitly available, we can infer their dedication through their actions and focus areas. The company's commitment to innovation, patient-centricity, and collaboration is evident in its pursuit of allogeneic CAR T-cell therapies.

Allogene Therapeutics, Inc. is dedicated to unlocking the potential of allogeneic cell therapy to revolutionize the treatment of cancer. As of February 15, 2024, Allogene announced that the FDA had lifted the clinical hold on their AlloCAR T program. This pivotal moment underscores Allogene's commitment to overcoming regulatory hurdles and advancing its innovative therapies. The company focuses on developing readily available, off-the-shelf CAR T-cell therapies, aiming to provide more patients with access to this potentially life-saving treatment option. Allogene's pipeline includes several AlloCAR T product candidates targeting various hematologic malignancies and solid tumors.

Here's a look at values that drive Allogene Therapeutics:

Innovation:

Allogene emphasizes innovation in the biotechnology sector. Evident in their pioneering work with AlloCAR T therapies, which are designed to be off-the-shelf, allogeneic CAR T-cell therapies, aiming to overcome the limitations of autologous CAR T-cell therapies, such as manufacturing complexities and prolonged wait times. According to their 2024 report, Allogene has made significant investments in research and development, allocating $242.7 million in 2023, compared to $285.8 million in 2022. These investments fuel the discovery and advancement of novel cell therapies, reflecting a commitment to pushing the boundaries of scientific knowledge and improving patient outcomes.

Patient-Centricity:

Allogene is committed to improving the lives of patients with cancer. This is demonstrated through their focus on developing therapies that are more accessible and convenient for patients. The AlloCAR T platform aims to provide an off-the-shelf product, reducing the need for personalized manufacturing and enabling faster treatment initiation. Allogene actively engages with patient advocacy groups and incorporates patient perspectives into their clinical trial design and development programs. In 2023, Allogene reported expenses of $29.9 million for research and development. This patient-centric approach is also reflected in their efforts to address unmet medical needs and develop therapies for underserved patient populations.

Collaboration:

Allogene recognizes the importance of collaboration in achieving its mission. Allogene fosters strategic partnerships with leading academic institutions, research organizations, and industry partners to leverage expertise and resources. For example, Allogene collaborates with the University of California, San Francisco (UCSF) to advance cell therapy research and development. These collaborations enable Allogene to accelerate innovation, expand its pipeline, and strengthen its position as a leader in the field of allogeneic cell therapy. In 2023, Allogene’s general and administrative expenses totaled $98.9 million. These collaborations are essential for driving progress and delivering transformative therapies to patients in need.

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