Cabaletta Bio, Inc. (CABA) Bundle
An Overview of Cabaletta Bio, Inc. (CABA)
General Summary of Cabaletta Bio, Inc. (CABA)
Cabaletta Bio, Inc. is a clinical-stage biotechnology company focused on developing engineered T cell therapies for autoimmune diseases. Founded in 2017 and headquartered in Philadelphia, Pennsylvania.
Company Products and Services
Primary focus on developing CABA-201, an investigational anti-CD19 chimeric autoantibody receptor (CAAR) T cell therapy platform targeting autoimmune diseases.
Financial Performance
Financial Metric | 2023 Value |
---|---|
Total Revenue | $12.4 million |
Net Loss | ($73.2 million) |
Research & Development Expenses | $54.3 million |
Cash and Cash Equivalents | $199.7 million |
Key Clinical Development Highlights
- Ongoing Phase 1 trial for CABA-201 in mucosal pemphigus vulgaris
- Advancing CAAR T cell therapy platform
- Multiple preclinical programs in autoimmune diseases
Market Position
Cabaletta Bio is positioned as an innovative leader in autoimmune disease cell therapy, with a unique CAAR T cell technology platform targeting specific autoantibody-mediated diseases.
Mission Statement of Cabaletta Bio, Inc. (CABA)
Mission Statement of Cabaletta Bio, Inc. (CABA)
Cabaletta Bio, Inc. focuses on developing targeted B cell therapies for autoimmune diseases.
Core Mission Components
Component | Specific Details |
---|---|
Scientific Innovation | Developing DeCART (Degenerative Chimeric Antigen Receptor T) therapeutic platforms |
Target Diseases | Myasthenia gravis, systemic lupus erythematosus, pemphigus vulgaris |
Research Investment | $39.2 million allocated for R&D in 2023 |
Strategic Research Objectives
- Develop precision B cell immunotherapies
- Target specific autoimmune disease mechanisms
- Advance clinical-stage therapeutic candidates
Clinical Development Pipeline
Program | Stage | Target Indication |
---|---|---|
CABA-201 | Phase 1/2 | Myasthenia gravis |
CABA-202 | Preclinical | Systemic lupus erythematosus |
Financial Performance Metrics
Net loss for fiscal year 2023: $54.3 million
Cash and cash equivalents as of December 31, 2023: $146.7 million
Research Collaboration
- Partnerships with 3 academic research institutions
- 6 active research collaboration agreements
Vision Statement of Cabaletta Bio, Inc. (CABA)
Vision Statement of Cabaletta Bio, Inc. (CABA)
Precision Immunotherapeutics FocusCabaletta Bio's vision centers on developing targeted B cell immunotherapies for autoimmune diseases. As of Q4 2023, the company concentrated on precision medicine approaches targeting specific autoimmune conditions.
Key Research TargetsDisease Area | Research Stage | Clinical Development Status |
---|---|---|
Mucosal Pemphigus Vulgaris | Phase 1/2 Clinical Trial | CABA-201 Ongoing |
Generalized Myasthenia Gravis | Phase 2 Clinical Trial | CABA-202 Active |
- Develop novel CART-cell therapies for autoimmune disorders
- Advance precision immunotherapeutic platforms
- Target B cell dysfunction mechanisms
As of December 31, 2023: Research and development expenses: $46.3 million Cash and cash equivalents: $157.4 million
Technological Innovation MetricsInnovation Parameter | 2023 Performance |
---|---|
Patent Applications | 7 new filings |
Research Personnel | 58 specialized scientists |
Core Values of Cabaletta Bio, Inc. (CABA)
Core Values of Cabaletta Bio, Inc. (CABA)
Innovation and Scientific Excellence
Cabaletta Bio demonstrates commitment to innovation through its focus on B cell engineering and targeted cell therapies.
R&D Investment | Research Focus |
---|---|
$48.3 million (2023 fiscal year) | Chimeric Autoantigen Receptor (CAR) T cell therapies |
Patient-Centered Approach
Commitment to addressing unmet medical needs in autoimmune diseases.
- Clinical trials targeting CADR-T cell therapies
- Focus on pemphigus and other autoimmune disorders
Collaborative Research and Development
Strategic partnerships and collaborative research initiatives.
Research Collaborations | Partnership Details |
---|---|
3 active academic partnerships | Institutions focused on immunology research |
Ethical and Transparent Operations
Commitment to scientific integrity and transparent research practices.
- Adherence to FDA clinical trial guidelines
- Comprehensive regulatory compliance
Talent Development and Workplace Culture
Investment in scientific talent and organizational development.
Workforce Metrics | Details |
---|---|
Total employees: 112 | 84% with advanced scientific degrees |
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