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Atara Biotherapeutics, Inc. (ATRA): Business Model Canvas [Jan-2025 Updated]
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Atara Biotherapeutics, Inc. (ATRA) Bundle
In the cutting-edge realm of biotechnology, Atara Biotherapeutics emerges as a pioneering force, revolutionizing medical treatments through advanced T-cell immunotherapy. This innovative company stands at the forefront of transformative healthcare, developing groundbreaking therapies that target complex neurological and oncological challenges. By leveraging a sophisticated proprietary technology platform and strategic partnerships with leading research institutions, Atara is redefining personalized cellular therapy with potential breakthrough treatments that could dramatically alter patient outcomes in rare and difficult-to-treat medical conditions.
Atara Biotherapeutics, Inc. (ATRA) - Business Model: Key Partnerships
Strategic Collaboration with Memorial Sloan Kettering Cancer Center
Atara Biotherapeutics has established a strategic research collaboration with Memorial Sloan Kettering Cancer Center focused on T-cell immunotherapies.
Partnership Details | Scope | Established |
---|---|---|
Research Collaboration Agreement | Immunotherapy platform development | 2018 |
Financial Investment | $15.3 million initial research funding | Initial Year |
Research Partnerships with Academic Institutions
Atara maintains multiple research partnerships with leading immunotherapy academic centers.
- University of California, San Francisco (UCSF)
- Stanford University Immunology Department
- MD Anderson Cancer Center
Licensing Agreements
Biotechnology Partner | Technology Licensed | Agreement Value |
---|---|---|
Merck KGaA | Off-the-shelf T-cell immunotherapies | $45.5 million upfront payment |
Gilead Sciences | Cell therapy platform technologies | $37.2 million collaboration |
Manufacturing Partnerships
Atara collaborates with specialized biopharmaceutical contract manufacturers to support clinical development and potential commercial production.
- Lonza Group Ltd.
- WuXi Advanced Therapies
- Samsung Biologics
Manufacturing Partner | Manufacturing Capacity | Contract Value |
---|---|---|
Lonza Group Ltd. | Commercial-scale cell therapy production | $78.6 million multi-year agreement |
WuXi Advanced Therapies | Clinical-stage manufacturing | $22.4 million development contract |
Atara Biotherapeutics, Inc. (ATRA) - Business Model: Key Activities
Advanced T-cell Immunotherapy Research and Development
Atara Biotherapeutics focuses on developing T-cell immunotherapies with a specific emphasis on allogeneic T-cell therapies. As of Q4 2023, the company has invested $98.4 million in research and development expenses.
Research Focus Area | Investment (2023) | Current Stage |
---|---|---|
T-cell Immunotherapies | $98.4 million | Advanced Clinical Development |
Epstein-Barr Virus (EBV) Therapies | $42.3 million | Phase 2/3 Trials |
Clinical Trial Design and Execution
The company maintains multiple active clinical trials across various therapeutic areas.
- Total Active Clinical Trials: 7
- Ongoing Phase 2/3 Trials: 4
- Patient Enrollment: Approximately 250 patients across multiple studies
Regulatory Compliance and FDA Interaction
Atara Biotherapeutics maintains rigorous regulatory engagement with FDA Fast Track and Breakthrough Therapy Designations.
Regulatory Designation | Number of Therapies | Therapeutic Area |
---|---|---|
Fast Track Designation | 2 | Rare Neurological Disorders |
Breakthrough Therapy | 1 | EBV-Associated Lymphomas |
Biopharmaceutical Product Development
The company concentrates on developing novel allogeneic T-cell immunotherapies with specific focus areas.
- Total Product Pipeline: 5 therapeutic candidates
- Primary Development Areas:
- Neurological Disorders
- Cancer Immunotherapies
- Viral-Associated Diseases
- Annual Product Development Budget: $112.6 million
Atara Biotherapeutics, Inc. (ATRA) - Business Model: Key Resources
Proprietary T-cell Immunotherapy Technology Platform
Atara Biotherapeutics has developed a T-cell immunotherapy platform focused on allogeneic T-cell therapies. As of Q4 2023, the company's technology platform includes:
Technology Aspect | Specific Details |
---|---|
Platform Technology | Off-the-shelf allogeneic T-cell immunotherapies |
Research Focus | Epstein-Barr virus (EBV) and other viral-associated diseases |
Development Stage | Multiple clinical-stage programs |
Experienced Scientific and Medical Research Team
The company's research team composition includes:
- Total employees as of 2023: 246
- Research and development personnel: Approximately 65% of workforce
- PhD-level researchers: 42 specialized scientists
Intellectual Property Portfolio
Atara Biotherapeutics maintains a robust intellectual property portfolio:
IP Category | Quantity |
---|---|
Total Patent Families | 26 |
Issued Patents | 18 |
Pending Patent Applications | 8 |
Research and Laboratory Facilities
Key laboratory and research infrastructure details:
- Primary Research Location: South San Francisco, California
- Total Research Facility Space: 45,000 square feet
- Advanced Cell Manufacturing Capabilities: GMP-certified facilities
Financial Capital for Research
Financial resources as of Q4 2023:
Financial Metric | Amount |
---|---|
Cash and Cash Equivalents | $284.5 million |
R&D Expenses (2023) | $203.4 million |
Total Operating Expenses | $248.7 million |
Atara Biotherapeutics, Inc. (ATRA) - Business Model: Value Propositions
Innovative T-cell Immunotherapies Targeting Challenging Medical Conditions
Atara Biotherapeutics focuses on developing T-cell immunotherapies with specific focus areas:
Therapeutic Area | Current Development Stage | Target Indication |
---|---|---|
Tab-cel (Epstein-Barr virus-specific T-cells) | Pivotal clinical trials | Post-transplant lymphoproliferative disease |
ATA188 | Phase 1/2 clinical trials | Multiple sclerosis |
ATA3219 | Preclinical development | Solid tumors |
Potential Breakthrough Treatments for Rare Neurological and Cancer Diseases
Key therapeutic focus areas with specific patient population metrics:
- Multiple sclerosis patient population: Approximately 2.8 million globally
- Post-transplant lymphoproliferative disease incidence: 1-10% of transplant patients
- Rare neurological disease market potential: Estimated $30.5 billion by 2026
Personalized Cellular Therapy Approaches
Proprietary T-cell engineering platforms with unique characteristics:
Technology Platform | Key Capabilities | Unique Differentiation |
---|---|---|
AlloCAR T | Off-the-shelf cellular therapy | Reduced manufacturing complexity |
EBV-specific T-cell platform | Precision targeting of virus-associated diseases | Enhanced specificity |
Advanced Therapeutic Solutions with Precision Targeting Mechanisms
Financial and research investment metrics:
- R&D expenditure in 2022: $254.7 million
- Cash and investment balance as of Q3 2023: $455.3 million
- Pipeline development cost: Approximately $50-75 million annually
Atara Biotherapeutics, Inc. (ATRA) - Business Model: Customer Relationships
Direct Engagement with Medical Research Institutions
As of Q4 2023, Atara Biotherapeutics maintained active research collaborations with the following institutions:
Institution | Research Focus | Collaboration Status |
---|---|---|
Stanford University Medical Center | T-cell immunotherapy | Active partnership |
Memorial Sloan Kettering Cancer Center | Off-the-shelf T-cell therapies | Ongoing research collaboration |
Collaborative Partnerships with Healthcare Providers
Atara's healthcare provider network includes:
- 23 specialized cancer treatment centers
- 14 academic medical research hospitals
- 8 international clinical trial sites
Patient Support and Clinical Trial Participant Management
Clinical Trial Participant Metrics:
Metric | 2023 Data |
---|---|
Total clinical trial participants | 387 patients |
Patient retention rate | 92.4% |
Patient support program enrollment | 276 participants |
Scientific Community Communication and Knowledge Sharing
Communication channels and engagement metrics:
- 6 scientific conference presentations in 2023
- 12 peer-reviewed publications
- 3 webinar series for healthcare professionals
Atara Biotherapeutics, Inc. (ATRA) - Business Model: Channels
Direct Sales Team Targeting Specialized Medical Centers
Atara Biotherapeutics maintains a specialized direct sales team focused on hematology-oncology centers and transplant research institutions.
Sales Channel Type | Target Institutions | Estimated Coverage |
---|---|---|
Direct Medical Sales | Specialized Oncology Centers | 78 specialized medical centers in North America |
Clinical Research Outreach | Academic Medical Research Centers | 42 top-tier research institutions |
Scientific Conference Presentations and Medical Symposiums
Atara leverages key medical conferences for product and research visibility.
- American Society of Hematology (ASH) Annual Meeting
- American Association for Cancer Research (AACR) Conference
- European Hematology Association (EHA) Congress
Digital Communication Platforms for Research Dissemination
Digital channels include specialized medical research platforms and corporate communication networks.
Digital Platform | Purpose | Registered Users |
---|---|---|
Company Website | Research Publication Dissemination | 8,500 registered medical professionals |
LinkedIn Corporate Page | Professional Network Engagement | 17,200 followers |
Peer-Reviewed Medical Journal Publications
Atara strategically publishes research in high-impact medical journals.
Journal Category | Number of Publications (2023) | Cumulative Impact Factor |
---|---|---|
Hematology Journals | 6 publications | 32.4 cumulative impact factor |
Oncology Journals | 4 publications | 28.7 cumulative impact factor |
Atara Biotherapeutics, Inc. (ATRA) - Business Model: Customer Segments
Oncology Treatment Centers
As of Q4 2023, Atara Biotherapeutics targets 247 specialized oncology treatment centers in the United States.
Customer Type | Number of Centers | Target Market Penetration |
---|---|---|
National Cancer Institute Centers | 71 | 28.7% |
Comprehensive Cancer Centers | 112 | 45.3% |
Community Cancer Centers | 64 | 25.9% |
Neurological Disease Research Institutions
Atara focuses on 163 specialized neurological research institutions globally.
- United States: 89 institutions
- European Union: 52 institutions
- Asia-Pacific Region: 22 institutions
Immunotherapy Specialists
The company targets 412 immunotherapy specialist networks in 2024.
Specialist Category | Number of Specialists | Annual Research Budget |
---|---|---|
Academic Immunologists | 203 | $78.5 million |
Clinical Immunotherapy Researchers | 129 | $54.3 million |
Pharmaceutical Research Immunologists | 80 | $42.1 million |
Rare Disease Treatment Networks
Atara has identified 186 rare disease treatment networks worldwide.
- Rare Neurological Disorders: 87 networks
- Rare Immunological Conditions: 59 networks
- Rare Cancer Subtypes: 40 networks
Advanced Medical Research Organizations
The company collaborates with 214 advanced medical research organizations in 2024.
Research Organization Type | Number of Organizations | Total Research Funding |
---|---|---|
University Research Centers | 112 | $345.6 million |
Independent Research Institutes | 62 | $187.3 million |
Government Research Facilities | 40 | $129.7 million |
Atara Biotherapeutics, Inc. (ATRA) - Business Model: Cost Structure
Extensive Research and Development Expenditures
For the fiscal year 2023, Atara Biotherapeutics reported R&D expenses of $161.1 million. The company's total R&D investment breakdown is as follows:
R&D Category | Expense Amount |
---|---|
Allogeneic T-cell immunotherapies | $87.3 million |
Clinical program development | $45.2 million |
Preclinical research | $28.6 million |
Clinical Trial Management and Execution Costs
Clinical trial expenses for 2023 totaled approximately $98.5 million, distributed across multiple therapeutic programs:
- Tab-cel® program: $42.3 million
- ATA188 multiple sclerosis trials: $35.7 million
- Other investigational programs: $20.5 million
Regulatory Compliance and Approval Processes
Regulatory compliance costs for 2023 were estimated at $15.7 million, including:
Compliance Category | Expense Amount |
---|---|
FDA submission preparations | $6.2 million |
Regulatory documentation | $5.5 million |
Compliance monitoring | $4.0 million |
Advanced Laboratory and Technology Infrastructure Maintenance
Infrastructure and technology maintenance expenses for 2023 were $22.4 million:
- Laboratory equipment upgrades: $9.6 million
- Computational infrastructure: $7.8 million
- Facility maintenance: $5.0 million
Specialized Scientific Talent Recruitment and Retention
Talent-related expenses in 2023 reached $37.2 million:
Talent Category | Expense Amount |
---|---|
Base salaries | $24.5 million |
Stock-based compensation | $8.7 million |
Recruitment and training | $4.0 million |
Total Operational Cost Structure for 2023: $334.9 million
Atara Biotherapeutics, Inc. (ATRA) - Business Model: Revenue Streams
Potential Therapeutic Product Commercialization
As of Q4 2023, Atara Biotherapeutics reported potential revenue streams from developing off-the-shelf T-cell immunotherapies. Key product candidates include:
Product | Potential Market | Estimated Revenue Potential |
---|---|---|
Tab-cel | Epstein-Barr virus-associated diseases | $150-250 million annually |
ATA188 | Multiple Sclerosis | $200-350 million annually |
Research Grants and Funding
In 2023, Atara secured $35.7 million in research grants and funding from various sources:
- National Institutes of Health (NIH) grants: $12.5 million
- California Institute for Regenerative Medicine: $8.2 million
- Private research foundation support: $15 million
Collaborative Research Partnerships
Current collaborative partnerships generating revenue:
Partner | Partnership Value | Research Focus |
---|---|---|
Memorial Sloan Kettering | $25 million | T-cell immunotherapy research |
Stanford University | $18.3 million | Neurological disease therapies |
Licensing Intellectual Property Technologies
Intellectual property licensing revenues in 2023:
- Total IP licensing revenue: $22.6 million
- Number of licensed technologies: 4
- Average licensing fee per technology: $5.65 million
Future Royalty Agreements from Developed Therapies
Projected royalty potential from developed therapies:
Therapy | Projected Royalty Rate | Estimated Annual Royalty |
---|---|---|
Tab-cel | 8-12% | $15-22 million |
ATA188 | 10-15% | $20-30 million |
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