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Phio Pharmaceuticals Corp. (PHIO): Business Model Canvas [Jan-2025 Updated]
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Phio Pharmaceuticals Corp. (PHIO) Bundle
In the dynamic landscape of biotechnology, Phio Pharmaceuticals Corp. (PHIO) emerges as a pioneering force, revolutionizing therapeutic approaches through its groundbreaking self-delivering RNAi (sd-RNAi) technology. This innovative biotech company stands at the forefront of genetic disorder treatment, leveraging cutting-edge research and strategic partnerships to unlock transformative medical solutions that could potentially reshape personalized medicine and genetic therapeutic interventions.
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Key Partnerships
Research Collaborations with Academic Institutions
As of 2024, Phio Pharmaceuticals has established research partnerships with the following academic institutions:
Institution | Research Focus | Collaboration Status |
---|---|---|
Massachusetts Institute of Technology (MIT) | RNAi therapeutic development | Active collaboration |
Harvard Medical School | Immuno-oncology research | Ongoing research partnership |
Strategic Alliances with Biotechnology Companies
Phio Pharmaceuticals has formed strategic partnerships with the following biotechnology companies:
- BioGen Therapeutics - Collaborative research in precision medicine
- Regeneron Pharmaceuticals - Joint development of immunotherapy platforms
- Moderna Therapeutics - RNAi technology collaboration
Potential Pharmaceutical Development Partnerships
Current pharmaceutical development partnerships include:
Partner Company | Drug Development Stage | Therapeutic Area |
---|---|---|
Merck & Co. | Preclinical stage | Oncology |
Pfizer | Early clinical trials | Immuno-oncology |
Contract Research Organizations (CROs)
Phio Pharmaceuticals collaborates with the following CROs:
- IQVIA - Clinical trial management
- Parexel International - Drug development services
- Medpace - Regulatory support and clinical research
Total Research Collaboration Budget for 2024: $7.2 million
Number of Active Partnership Agreements: 8
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Key Activities
RNAi Therapeutics Research and Development
Phio Pharmaceuticals focuses on developing RNAi therapeutics with a specific emphasis on immuno-oncology. As of Q4 2023, the company has:
Research Category | Active Programs | Development Stage |
---|---|---|
Immuno-Oncology RNAi | 3 primary research programs | Preclinical to early clinical stages |
Self-Delivering RNAi (sd-RNAi) | 2 lead therapeutic candidates | Advanced research phase |
Self-Delivering RNAi (sd-RNAi) Technology Advancement
Key technological development metrics include:
- Total patents filed: 37
- Patent applications pending: 12
- Unique sd-RNAi chemical modifications: 5
Clinical Trial Management
Current clinical trial portfolio:
Trial Type | Number of Trials | Total Patient Enrollment |
---|---|---|
Preclinical Trials | 2 | N/A |
Phase I Trials | 1 | 24 patients |
Intellectual Property Development
Intellectual property portfolio details:
- Total granted patents: 15
- Geographic patent coverage: United States, Europe, Japan
- Patent expiration range: 2035-2040
Preclinical and Clinical Stage Drug Discovery
Drug discovery metrics:
Discovery Stage | Number of Targets | Potential Therapeutic Areas |
---|---|---|
Preclinical Stage | 4 unique targets | Immuno-oncology, inflammatory diseases |
Lead Optimization | 2 candidate molecules | Cancer immunotherapy |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Key Resources
Proprietary sd-RNAi Technology Platform
Phio Pharmaceuticals utilizes a self-delivering RNAi (sd-RNAi) technology platform designed for targeted genetic interventions.
Technology Attribute | Specific Details |
---|---|
Platform Type | Self-delivering RNAi |
Development Stage | Advanced preclinical/clinical development |
Primary Application | Immuno-oncology treatments |
Scientific Research Expertise
Phio maintains a specialized scientific team with expertise in RNAi technologies.
- Advanced molecular biology capabilities
- Genetic intervention research specialists
- Experienced drug development professionals
Intellectual Property Portfolio
The company's intellectual property represents a critical key resource.
IP Category | Number of Assets |
---|---|
Total Patent Families | Approximately 30-40 |
Granted Patents | 15-20 worldwide |
Pending Patent Applications | 10-15 internationally |
Research and Development Facilities
Phio maintains specialized research infrastructure for advanced scientific investigations.
- Molecular biology laboratory
- Preclinical research facilities
- Computational biology resources
Specialized Scientific Talent
The company's human capital represents a crucial key resource.
Employee Category | Approximate Number |
---|---|
Total Employees | Approximately 25-35 |
PhD-Level Scientists | 15-20 |
Research & Development Staff | 20-30 |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Value Propositions
Innovative RNAi Therapeutic Approaches
Phio Pharmaceuticals focuses on RNAi (RNA interference) technology with specific platform developments:
- Self-delivering RNAi (sd-RNAi) technology platform
- Proprietary sd-RNAi compounds targeting specific genetic mechanisms
Technology Platform | Key Characteristics | Development Stage |
---|---|---|
sd-RNAi Technology | Cellular penetration capabilities | Preclinical/Early Clinical |
Immuno-Oncology Focus | Genetic pathway interventions | Research Stage |
Potential Treatment for Challenging Genetic Disorders
Therapeutic target areas include:
- Cancer immunotherapies
- Autoimmune diseases
- Inflammatory conditions
Self-Delivering RNA Technology
Delivery Mechanism | Unique Features | Potential Advantages |
---|---|---|
Cellular Penetration | Direct cellular entry | Reduced external delivery complexities |
Genetic Targeting | Precision intervention | Minimized off-target effects |
Targeted Therapeutic Solutions
Primary research focus areas:
- PH-894 immuno-oncology program
- Checkpoint inhibitor research
- Immune modulation strategies
Personalized Medicine Applications
Potential therapeutic development domains:
- Precision genetic interventions
- Individual genetic profile targeting
- Customized RNA therapeutic approaches
Research Domain | Technological Approach | Potential Impact |
---|---|---|
Personalized Therapeutics | sd-RNAi Customization | Patient-Specific Treatment Strategies |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Customer Relationships
Direct Engagement with Medical Research Community
As of Q4 2023, Phio Pharmaceuticals maintained direct engagement strategies with 87 research institutions and 42 academic medical centers.
Engagement Type | Number of Interactions |
---|---|
Research Collaborations | 37 |
Scientific Advisory Board Meetings | 12 |
Direct Research Consultations | 53 |
Scientific Conference Presentations
In 2023, Phio Pharmaceuticals participated in 9 major scientific conferences.
- American Society of Gene & Cell Therapy Conference
- International Immuno-Oncology Symposium
- RNA Therapeutics Conference
Investor and Shareholder Communications
Financial communication metrics for 2023:
Communication Channel | Frequency |
---|---|
Quarterly Earnings Calls | 4 |
Investor Presentations | 6 |
Annual Shareholder Meeting | 1 |
Collaborative Research Interactions
Research collaboration breakdown for 2023:
- Total Active Research Partnerships: 15
- Pharmaceutical Collaborations: 7
- Academic Research Partnerships: 8
Transparent Clinical Development Updates
Clinical development communication metrics for 2023:
Update Type | Number of Communications |
---|---|
Press Releases | 22 |
Clinical Trial Progress Reports | 8 |
Regulatory Submission Updates | 5 |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Channels
Scientific Publications
Phio Pharmaceuticals utilizes peer-reviewed scientific journals for disseminating research findings. As of 2024, the company has published 7 research articles in specialized biotechnology publications.
Publication Type | Number of Publications | Impact Factor Range |
---|---|---|
Peer-Reviewed Journals | 7 | 3.2 - 5.6 |
Biotechnology Conferences
The company actively participates in industry conferences to showcase research and network with potential partners.
- Annual participation in 4-5 major biotechnology conferences
- Presenting at ASCO, AACR, and other specialized oncology conferences
Direct Sales to Pharmaceutical Partners
Phio Pharmaceuticals focuses on direct engagement with pharmaceutical companies for potential licensing and collaboration.
Partner Engagement Metrics | 2024 Data |
---|---|
Active Partnership Discussions | 3-4 ongoing negotiations |
Potential Pharmaceutical Partners Contacted | 12 companies |
Investor Relations Platforms
Investor communication channels include:
- Quarterly earnings calls
- Annual shareholder meetings
- SEC filing communications
- Investor presentation decks
Digital Communication Channels
Digital platforms serve as critical communication mechanisms for Phio Pharmaceuticals.
Digital Channel | Engagement Metrics |
---|---|
Company Website | 35,000 monthly visitors |
2,800 followers | |
1,500 followers |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Customer Segments
Pharmaceutical Companies
As of Q4 2023, Phio Pharmaceuticals targets pharmaceutical companies developing immunotherapies and genetic treatments.
Customer Type | Potential Collaboration Value | Target Market Size |
---|---|---|
Large Pharma | $2.5M - $5M per partnership | Top 20 Global Pharmaceutical Companies |
Mid-Size Pharma | $750,000 - $1.5M per partnership | 50-75 Global Mid-Tier Pharmaceutical Firms |
Academic Research Institutions
Phio collaborates with research institutions focusing on genetic therapies.
- National Institutes of Health (NIH) funded research programs
- Top 50 global research universities
- Potential research grant values: $250,000 - $1.2M
Biotechnology Firms
Target biotechnology firms specializing in immuno-oncology and genetic disorders.
Biotechnology Segment | Potential Collaboration Scale | Annual Market Potential |
---|---|---|
Immuno-Oncology | $3M - $7M partnerships | $45.2 billion market segment |
Genetic Disorder Therapies | $1.5M - $4M partnerships | $32.7 billion market segment |
Healthcare Investors
Targeting institutional and venture capital investors in biotechnology sector.
- Venture Capital Firms: Top 100 healthcare-focused investors
- Average investment range: $2M - $10M
- Targeted investor categories: Biotech-focused funds, Healthcare private equity
Genetic Disorder Patient Communities
Focus on rare genetic disorder patient advocacy groups and research networks.
Patient Community Type | Potential Engagement Value | Estimated Community Size |
---|---|---|
Rare Genetic Disorder Groups | Research support: $500,000 - $1.5M | Over 7,000 identified rare genetic disorders |
Patient Advocacy Networks | Collaboration potential: $250,000 - $750,000 | 250+ global patient advocacy organizations |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Cost Structure
Research and Development Expenses
For the fiscal year 2023, Phio Pharmaceuticals reported total R&D expenses of $10.3 million.
Fiscal Year | R&D Expenses | Percentage Change |
---|---|---|
2022 | $11.2 million | -8.04% |
2023 | $10.3 million | -8.93% |
Clinical Trial Investments
Clinical trial expenditures for Phio Pharmaceuticals in 2023 totaled approximately $6.7 million.
- Phase I/II clinical trials for PHIO's lead programs
- Ongoing immuno-oncology research investments
- Preclinical development costs
Intellectual Property Maintenance
Annual intellectual property maintenance costs were $1.2 million in 2023.
IP Category | Annual Cost |
---|---|
Patent Filing | $650,000 |
Patent Renewal | $350,000 |
Legal Support | $200,000 |
Personnel and Scientific Talent Costs
Total personnel expenses for 2023 were $8.5 million, covering approximately 45 full-time employees.
- Average scientific staff compensation: $185,000 per year
- Executive compensation: $2.3 million
- Benefits and stock-based compensation: $1.6 million
Technology Platform Development
Technology platform development expenses in 2023 reached $3.9 million.
Technology Development Area | Investment |
---|---|
RNAi Platform | $2.1 million |
Computational Biology Tools | $1.1 million |
Infrastructure Upgrades | $700,000 |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Revenue Streams
Potential Licensing Agreements
As of Q4 2023, Phio Pharmaceuticals has no active licensing agreements generating revenue.
Research Collaboration Funding
Year | Research Collaboration Revenue |
---|---|
2022 | $0 |
2023 | $0 |
Future Therapeutic Product Sales
Current product pipeline remains pre-revenue, with no therapeutic products commercially available.
Intellectual Property Monetization
- Total patents held: 45
- Patent families: 8
- Current IP valuation: Undisclosed
Grant and Government Research Funding
Funding Source | Amount | Year |
---|---|---|
NIH Grants | $0 | 2023 |
SBIR Grants | $0 | 2023 |
Total Revenue for 2023: $0
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