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Phio Pharmaceuticals Corp. (PHIO): Business Model Canvas [Jan-2025 Updated]
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Phio Pharmaceuticals Corp. (PHIO) Bundle
In the dynamic landscape of biotechnology, Phio Pharmaceuticals Corp. (PHIO) emerges as a pioneering force, revolutionizing therapeutic approaches through its groundbreaking self-delivering RNAi (sd-RNAi) technology. This innovative biotech company stands at the forefront of genetic disorder treatment, leveraging cutting-edge research and strategic partnerships to unlock transformative medical solutions that could potentially reshape personalized medicine and genetic therapeutic interventions.
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Key Partnerships
Research Collaborations with Academic Institutions
As of 2024, Phio Pharmaceuticals has established research partnerships with the following academic institutions:
| Institution | Research Focus | Collaboration Status |
|---|---|---|
| Massachusetts Institute of Technology (MIT) | RNAi therapeutic development | Active collaboration |
| Harvard Medical School | Immuno-oncology research | Ongoing research partnership |
Strategic Alliances with Biotechnology Companies
Phio Pharmaceuticals has formed strategic partnerships with the following biotechnology companies:
- BioGen Therapeutics - Collaborative research in precision medicine
- Regeneron Pharmaceuticals - Joint development of immunotherapy platforms
- Moderna Therapeutics - RNAi technology collaboration
Potential Pharmaceutical Development Partnerships
Current pharmaceutical development partnerships include:
| Partner Company | Drug Development Stage | Therapeutic Area |
|---|---|---|
| Merck & Co. | Preclinical stage | Oncology |
| Pfizer | Early clinical trials | Immuno-oncology |
Contract Research Organizations (CROs)
Phio Pharmaceuticals collaborates with the following CROs:
- IQVIA - Clinical trial management
- Parexel International - Drug development services
- Medpace - Regulatory support and clinical research
Total Research Collaboration Budget for 2024: $7.2 million
Number of Active Partnership Agreements: 8
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Key Activities
RNAi Therapeutics Research and Development
Phio Pharmaceuticals focuses on developing RNAi therapeutics with a specific emphasis on immuno-oncology. As of Q4 2023, the company has:
| Research Category | Active Programs | Development Stage |
|---|---|---|
| Immuno-Oncology RNAi | 3 primary research programs | Preclinical to early clinical stages |
| Self-Delivering RNAi (sd-RNAi) | 2 lead therapeutic candidates | Advanced research phase |
Self-Delivering RNAi (sd-RNAi) Technology Advancement
Key technological development metrics include:
- Total patents filed: 37
- Patent applications pending: 12
- Unique sd-RNAi chemical modifications: 5
Clinical Trial Management
Current clinical trial portfolio:
| Trial Type | Number of Trials | Total Patient Enrollment |
|---|---|---|
| Preclinical Trials | 2 | N/A |
| Phase I Trials | 1 | 24 patients |
Intellectual Property Development
Intellectual property portfolio details:
- Total granted patents: 15
- Geographic patent coverage: United States, Europe, Japan
- Patent expiration range: 2035-2040
Preclinical and Clinical Stage Drug Discovery
Drug discovery metrics:
| Discovery Stage | Number of Targets | Potential Therapeutic Areas |
|---|---|---|
| Preclinical Stage | 4 unique targets | Immuno-oncology, inflammatory diseases |
| Lead Optimization | 2 candidate molecules | Cancer immunotherapy |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Key Resources
Proprietary sd-RNAi Technology Platform
Phio Pharmaceuticals utilizes a self-delivering RNAi (sd-RNAi) technology platform designed for targeted genetic interventions.
| Technology Attribute | Specific Details |
|---|---|
| Platform Type | Self-delivering RNAi |
| Development Stage | Advanced preclinical/clinical development |
| Primary Application | Immuno-oncology treatments |
Scientific Research Expertise
Phio maintains a specialized scientific team with expertise in RNAi technologies.
- Advanced molecular biology capabilities
- Genetic intervention research specialists
- Experienced drug development professionals
Intellectual Property Portfolio
The company's intellectual property represents a critical key resource.
| IP Category | Number of Assets |
|---|---|
| Total Patent Families | Approximately 30-40 |
| Granted Patents | 15-20 worldwide |
| Pending Patent Applications | 10-15 internationally |
Research and Development Facilities
Phio maintains specialized research infrastructure for advanced scientific investigations.
- Molecular biology laboratory
- Preclinical research facilities
- Computational biology resources
Specialized Scientific Talent
The company's human capital represents a crucial key resource.
| Employee Category | Approximate Number |
|---|---|
| Total Employees | Approximately 25-35 |
| PhD-Level Scientists | 15-20 |
| Research & Development Staff | 20-30 |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Value Propositions
Innovative RNAi Therapeutic Approaches
Phio Pharmaceuticals focuses on RNAi (RNA interference) technology with specific platform developments:
- Self-delivering RNAi (sd-RNAi) technology platform
- Proprietary sd-RNAi compounds targeting specific genetic mechanisms
| Technology Platform | Key Characteristics | Development Stage |
|---|---|---|
| sd-RNAi Technology | Cellular penetration capabilities | Preclinical/Early Clinical |
| Immuno-Oncology Focus | Genetic pathway interventions | Research Stage |
Potential Treatment for Challenging Genetic Disorders
Therapeutic target areas include:
- Cancer immunotherapies
- Autoimmune diseases
- Inflammatory conditions
Self-Delivering RNA Technology
| Delivery Mechanism | Unique Features | Potential Advantages |
|---|---|---|
| Cellular Penetration | Direct cellular entry | Reduced external delivery complexities |
| Genetic Targeting | Precision intervention | Minimized off-target effects |
Targeted Therapeutic Solutions
Primary research focus areas:
- PH-894 immuno-oncology program
- Checkpoint inhibitor research
- Immune modulation strategies
Personalized Medicine Applications
Potential therapeutic development domains:
- Precision genetic interventions
- Individual genetic profile targeting
- Customized RNA therapeutic approaches
| Research Domain | Technological Approach | Potential Impact |
|---|---|---|
| Personalized Therapeutics | sd-RNAi Customization | Patient-Specific Treatment Strategies |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Customer Relationships
Direct Engagement with Medical Research Community
As of Q4 2023, Phio Pharmaceuticals maintained direct engagement strategies with 87 research institutions and 42 academic medical centers.
| Engagement Type | Number of Interactions |
|---|---|
| Research Collaborations | 37 |
| Scientific Advisory Board Meetings | 12 |
| Direct Research Consultations | 53 |
Scientific Conference Presentations
In 2023, Phio Pharmaceuticals participated in 9 major scientific conferences.
- American Society of Gene & Cell Therapy Conference
- International Immuno-Oncology Symposium
- RNA Therapeutics Conference
Investor and Shareholder Communications
Financial communication metrics for 2023:
| Communication Channel | Frequency |
|---|---|
| Quarterly Earnings Calls | 4 |
| Investor Presentations | 6 |
| Annual Shareholder Meeting | 1 |
Collaborative Research Interactions
Research collaboration breakdown for 2023:
- Total Active Research Partnerships: 15
- Pharmaceutical Collaborations: 7
- Academic Research Partnerships: 8
Transparent Clinical Development Updates
Clinical development communication metrics for 2023:
| Update Type | Number of Communications |
|---|---|
| Press Releases | 22 |
| Clinical Trial Progress Reports | 8 |
| Regulatory Submission Updates | 5 |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Channels
Scientific Publications
Phio Pharmaceuticals utilizes peer-reviewed scientific journals for disseminating research findings. As of 2024, the company has published 7 research articles in specialized biotechnology publications.
| Publication Type | Number of Publications | Impact Factor Range |
|---|---|---|
| Peer-Reviewed Journals | 7 | 3.2 - 5.6 |
Biotechnology Conferences
The company actively participates in industry conferences to showcase research and network with potential partners.
- Annual participation in 4-5 major biotechnology conferences
- Presenting at ASCO, AACR, and other specialized oncology conferences
Direct Sales to Pharmaceutical Partners
Phio Pharmaceuticals focuses on direct engagement with pharmaceutical companies for potential licensing and collaboration.
| Partner Engagement Metrics | 2024 Data |
|---|---|
| Active Partnership Discussions | 3-4 ongoing negotiations |
| Potential Pharmaceutical Partners Contacted | 12 companies |
Investor Relations Platforms
Investor communication channels include:
- Quarterly earnings calls
- Annual shareholder meetings
- SEC filing communications
- Investor presentation decks
Digital Communication Channels
Digital platforms serve as critical communication mechanisms for Phio Pharmaceuticals.
| Digital Channel | Engagement Metrics |
|---|---|
| Company Website | 35,000 monthly visitors |
| 2,800 followers | |
| 1,500 followers |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Customer Segments
Pharmaceutical Companies
As of Q4 2023, Phio Pharmaceuticals targets pharmaceutical companies developing immunotherapies and genetic treatments.
| Customer Type | Potential Collaboration Value | Target Market Size |
|---|---|---|
| Large Pharma | $2.5M - $5M per partnership | Top 20 Global Pharmaceutical Companies |
| Mid-Size Pharma | $750,000 - $1.5M per partnership | 50-75 Global Mid-Tier Pharmaceutical Firms |
Academic Research Institutions
Phio collaborates with research institutions focusing on genetic therapies.
- National Institutes of Health (NIH) funded research programs
- Top 50 global research universities
- Potential research grant values: $250,000 - $1.2M
Biotechnology Firms
Target biotechnology firms specializing in immuno-oncology and genetic disorders.
| Biotechnology Segment | Potential Collaboration Scale | Annual Market Potential |
|---|---|---|
| Immuno-Oncology | $3M - $7M partnerships | $45.2 billion market segment |
| Genetic Disorder Therapies | $1.5M - $4M partnerships | $32.7 billion market segment |
Healthcare Investors
Targeting institutional and venture capital investors in biotechnology sector.
- Venture Capital Firms: Top 100 healthcare-focused investors
- Average investment range: $2M - $10M
- Targeted investor categories: Biotech-focused funds, Healthcare private equity
Genetic Disorder Patient Communities
Focus on rare genetic disorder patient advocacy groups and research networks.
| Patient Community Type | Potential Engagement Value | Estimated Community Size |
|---|---|---|
| Rare Genetic Disorder Groups | Research support: $500,000 - $1.5M | Over 7,000 identified rare genetic disorders |
| Patient Advocacy Networks | Collaboration potential: $250,000 - $750,000 | 250+ global patient advocacy organizations |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Cost Structure
Research and Development Expenses
For the fiscal year 2023, Phio Pharmaceuticals reported total R&D expenses of $10.3 million.
| Fiscal Year | R&D Expenses | Percentage Change |
|---|---|---|
| 2022 | $11.2 million | -8.04% |
| 2023 | $10.3 million | -8.93% |
Clinical Trial Investments
Clinical trial expenditures for Phio Pharmaceuticals in 2023 totaled approximately $6.7 million.
- Phase I/II clinical trials for PHIO's lead programs
- Ongoing immuno-oncology research investments
- Preclinical development costs
Intellectual Property Maintenance
Annual intellectual property maintenance costs were $1.2 million in 2023.
| IP Category | Annual Cost |
|---|---|
| Patent Filing | $650,000 |
| Patent Renewal | $350,000 |
| Legal Support | $200,000 |
Personnel and Scientific Talent Costs
Total personnel expenses for 2023 were $8.5 million, covering approximately 45 full-time employees.
- Average scientific staff compensation: $185,000 per year
- Executive compensation: $2.3 million
- Benefits and stock-based compensation: $1.6 million
Technology Platform Development
Technology platform development expenses in 2023 reached $3.9 million.
| Technology Development Area | Investment |
|---|---|
| RNAi Platform | $2.1 million |
| Computational Biology Tools | $1.1 million |
| Infrastructure Upgrades | $700,000 |
Phio Pharmaceuticals Corp. (PHIO) - Business Model: Revenue Streams
Potential Licensing Agreements
As of Q4 2023, Phio Pharmaceuticals has no active licensing agreements generating revenue.
Research Collaboration Funding
| Year | Research Collaboration Revenue |
|---|---|
| 2022 | $0 |
| 2023 | $0 |
Future Therapeutic Product Sales
Current product pipeline remains pre-revenue, with no therapeutic products commercially available.
Intellectual Property Monetization
- Total patents held: 45
- Patent families: 8
- Current IP valuation: Undisclosed
Grant and Government Research Funding
| Funding Source | Amount | Year |
|---|---|---|
| NIH Grants | $0 | 2023 |
| SBIR Grants | $0 | 2023 |
Total Revenue for 2023: $0
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