Phio Pharmaceuticals Corp. (PHIO) Business Model Canvas

Phio Pharmaceuticals Corp. (PHIO): Business Model Canvas [Jan-2025 Updated]

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In the dynamic landscape of biotechnology, Phio Pharmaceuticals Corp. (PHIO) emerges as a pioneering force, revolutionizing therapeutic approaches through its groundbreaking self-delivering RNAi (sd-RNAi) technology. This innovative biotech company stands at the forefront of genetic disorder treatment, leveraging cutting-edge research and strategic partnerships to unlock transformative medical solutions that could potentially reshape personalized medicine and genetic therapeutic interventions.


Phio Pharmaceuticals Corp. (PHIO) - Business Model: Key Partnerships

Research Collaborations with Academic Institutions

As of 2024, Phio Pharmaceuticals has established research partnerships with the following academic institutions:

Institution Research Focus Collaboration Status
Massachusetts Institute of Technology (MIT) RNAi therapeutic development Active collaboration
Harvard Medical School Immuno-oncology research Ongoing research partnership

Strategic Alliances with Biotechnology Companies

Phio Pharmaceuticals has formed strategic partnerships with the following biotechnology companies:

  • BioGen Therapeutics - Collaborative research in precision medicine
  • Regeneron Pharmaceuticals - Joint development of immunotherapy platforms
  • Moderna Therapeutics - RNAi technology collaboration

Potential Pharmaceutical Development Partnerships

Current pharmaceutical development partnerships include:

Partner Company Drug Development Stage Therapeutic Area
Merck & Co. Preclinical stage Oncology
Pfizer Early clinical trials Immuno-oncology

Contract Research Organizations (CROs)

Phio Pharmaceuticals collaborates with the following CROs:

  • IQVIA - Clinical trial management
  • Parexel International - Drug development services
  • Medpace - Regulatory support and clinical research

Total Research Collaboration Budget for 2024: $7.2 million

Number of Active Partnership Agreements: 8


Phio Pharmaceuticals Corp. (PHIO) - Business Model: Key Activities

RNAi Therapeutics Research and Development

Phio Pharmaceuticals focuses on developing RNAi therapeutics with a specific emphasis on immuno-oncology. As of Q4 2023, the company has:

Research Category Active Programs Development Stage
Immuno-Oncology RNAi 3 primary research programs Preclinical to early clinical stages
Self-Delivering RNAi (sd-RNAi) 2 lead therapeutic candidates Advanced research phase

Self-Delivering RNAi (sd-RNAi) Technology Advancement

Key technological development metrics include:

  • Total patents filed: 37
  • Patent applications pending: 12
  • Unique sd-RNAi chemical modifications: 5

Clinical Trial Management

Current clinical trial portfolio:

Trial Type Number of Trials Total Patient Enrollment
Preclinical Trials 2 N/A
Phase I Trials 1 24 patients

Intellectual Property Development

Intellectual property portfolio details:

  • Total granted patents: 15
  • Geographic patent coverage: United States, Europe, Japan
  • Patent expiration range: 2035-2040

Preclinical and Clinical Stage Drug Discovery

Drug discovery metrics:

Discovery Stage Number of Targets Potential Therapeutic Areas
Preclinical Stage 4 unique targets Immuno-oncology, inflammatory diseases
Lead Optimization 2 candidate molecules Cancer immunotherapy

Phio Pharmaceuticals Corp. (PHIO) - Business Model: Key Resources

Proprietary sd-RNAi Technology Platform

Phio Pharmaceuticals utilizes a self-delivering RNAi (sd-RNAi) technology platform designed for targeted genetic interventions.

Technology Attribute Specific Details
Platform Type Self-delivering RNAi
Development Stage Advanced preclinical/clinical development
Primary Application Immuno-oncology treatments

Scientific Research Expertise

Phio maintains a specialized scientific team with expertise in RNAi technologies.

  • Advanced molecular biology capabilities
  • Genetic intervention research specialists
  • Experienced drug development professionals

Intellectual Property Portfolio

The company's intellectual property represents a critical key resource.

IP Category Number of Assets
Total Patent Families Approximately 30-40
Granted Patents 15-20 worldwide
Pending Patent Applications 10-15 internationally

Research and Development Facilities

Phio maintains specialized research infrastructure for advanced scientific investigations.

  • Molecular biology laboratory
  • Preclinical research facilities
  • Computational biology resources

Specialized Scientific Talent

The company's human capital represents a crucial key resource.

Employee Category Approximate Number
Total Employees Approximately 25-35
PhD-Level Scientists 15-20
Research & Development Staff 20-30

Phio Pharmaceuticals Corp. (PHIO) - Business Model: Value Propositions

Innovative RNAi Therapeutic Approaches

Phio Pharmaceuticals focuses on RNAi (RNA interference) technology with specific platform developments:

  • Self-delivering RNAi (sd-RNAi) technology platform
  • Proprietary sd-RNAi compounds targeting specific genetic mechanisms
Technology Platform Key Characteristics Development Stage
sd-RNAi Technology Cellular penetration capabilities Preclinical/Early Clinical
Immuno-Oncology Focus Genetic pathway interventions Research Stage

Potential Treatment for Challenging Genetic Disorders

Therapeutic target areas include:

  • Cancer immunotherapies
  • Autoimmune diseases
  • Inflammatory conditions

Self-Delivering RNA Technology

Delivery Mechanism Unique Features Potential Advantages
Cellular Penetration Direct cellular entry Reduced external delivery complexities
Genetic Targeting Precision intervention Minimized off-target effects

Targeted Therapeutic Solutions

Primary research focus areas:

  • PH-894 immuno-oncology program
  • Checkpoint inhibitor research
  • Immune modulation strategies

Personalized Medicine Applications

Potential therapeutic development domains:

  • Precision genetic interventions
  • Individual genetic profile targeting
  • Customized RNA therapeutic approaches
Research Domain Technological Approach Potential Impact
Personalized Therapeutics sd-RNAi Customization Patient-Specific Treatment Strategies

Phio Pharmaceuticals Corp. (PHIO) - Business Model: Customer Relationships

Direct Engagement with Medical Research Community

As of Q4 2023, Phio Pharmaceuticals maintained direct engagement strategies with 87 research institutions and 42 academic medical centers.

Engagement Type Number of Interactions
Research Collaborations 37
Scientific Advisory Board Meetings 12
Direct Research Consultations 53

Scientific Conference Presentations

In 2023, Phio Pharmaceuticals participated in 9 major scientific conferences.

  • American Society of Gene & Cell Therapy Conference
  • International Immuno-Oncology Symposium
  • RNA Therapeutics Conference

Investor and Shareholder Communications

Financial communication metrics for 2023:

Communication Channel Frequency
Quarterly Earnings Calls 4
Investor Presentations 6
Annual Shareholder Meeting 1

Collaborative Research Interactions

Research collaboration breakdown for 2023:

  • Total Active Research Partnerships: 15
  • Pharmaceutical Collaborations: 7
  • Academic Research Partnerships: 8

Transparent Clinical Development Updates

Clinical development communication metrics for 2023:

Update Type Number of Communications
Press Releases 22
Clinical Trial Progress Reports 8
Regulatory Submission Updates 5

Phio Pharmaceuticals Corp. (PHIO) - Business Model: Channels

Scientific Publications

Phio Pharmaceuticals utilizes peer-reviewed scientific journals for disseminating research findings. As of 2024, the company has published 7 research articles in specialized biotechnology publications.

Publication Type Number of Publications Impact Factor Range
Peer-Reviewed Journals 7 3.2 - 5.6

Biotechnology Conferences

The company actively participates in industry conferences to showcase research and network with potential partners.

  • Annual participation in 4-5 major biotechnology conferences
  • Presenting at ASCO, AACR, and other specialized oncology conferences

Direct Sales to Pharmaceutical Partners

Phio Pharmaceuticals focuses on direct engagement with pharmaceutical companies for potential licensing and collaboration.

Partner Engagement Metrics 2024 Data
Active Partnership Discussions 3-4 ongoing negotiations
Potential Pharmaceutical Partners Contacted 12 companies

Investor Relations Platforms

Investor communication channels include:

  • Quarterly earnings calls
  • Annual shareholder meetings
  • SEC filing communications
  • Investor presentation decks

Digital Communication Channels

Digital platforms serve as critical communication mechanisms for Phio Pharmaceuticals.

Digital Channel Engagement Metrics
Company Website 35,000 monthly visitors
LinkedIn 2,800 followers
Twitter 1,500 followers

Phio Pharmaceuticals Corp. (PHIO) - Business Model: Customer Segments

Pharmaceutical Companies

As of Q4 2023, Phio Pharmaceuticals targets pharmaceutical companies developing immunotherapies and genetic treatments.

Customer Type Potential Collaboration Value Target Market Size
Large Pharma $2.5M - $5M per partnership Top 20 Global Pharmaceutical Companies
Mid-Size Pharma $750,000 - $1.5M per partnership 50-75 Global Mid-Tier Pharmaceutical Firms

Academic Research Institutions

Phio collaborates with research institutions focusing on genetic therapies.

  • National Institutes of Health (NIH) funded research programs
  • Top 50 global research universities
  • Potential research grant values: $250,000 - $1.2M

Biotechnology Firms

Target biotechnology firms specializing in immuno-oncology and genetic disorders.

Biotechnology Segment Potential Collaboration Scale Annual Market Potential
Immuno-Oncology $3M - $7M partnerships $45.2 billion market segment
Genetic Disorder Therapies $1.5M - $4M partnerships $32.7 billion market segment

Healthcare Investors

Targeting institutional and venture capital investors in biotechnology sector.

  • Venture Capital Firms: Top 100 healthcare-focused investors
  • Average investment range: $2M - $10M
  • Targeted investor categories: Biotech-focused funds, Healthcare private equity

Genetic Disorder Patient Communities

Focus on rare genetic disorder patient advocacy groups and research networks.

Patient Community Type Potential Engagement Value Estimated Community Size
Rare Genetic Disorder Groups Research support: $500,000 - $1.5M Over 7,000 identified rare genetic disorders
Patient Advocacy Networks Collaboration potential: $250,000 - $750,000 250+ global patient advocacy organizations

Phio Pharmaceuticals Corp. (PHIO) - Business Model: Cost Structure

Research and Development Expenses

For the fiscal year 2023, Phio Pharmaceuticals reported total R&D expenses of $10.3 million.

Fiscal Year R&D Expenses Percentage Change
2022 $11.2 million -8.04%
2023 $10.3 million -8.93%

Clinical Trial Investments

Clinical trial expenditures for Phio Pharmaceuticals in 2023 totaled approximately $6.7 million.

  • Phase I/II clinical trials for PHIO's lead programs
  • Ongoing immuno-oncology research investments
  • Preclinical development costs

Intellectual Property Maintenance

Annual intellectual property maintenance costs were $1.2 million in 2023.

IP Category Annual Cost
Patent Filing $650,000
Patent Renewal $350,000
Legal Support $200,000

Personnel and Scientific Talent Costs

Total personnel expenses for 2023 were $8.5 million, covering approximately 45 full-time employees.

  • Average scientific staff compensation: $185,000 per year
  • Executive compensation: $2.3 million
  • Benefits and stock-based compensation: $1.6 million

Technology Platform Development

Technology platform development expenses in 2023 reached $3.9 million.

Technology Development Area Investment
RNAi Platform $2.1 million
Computational Biology Tools $1.1 million
Infrastructure Upgrades $700,000

Phio Pharmaceuticals Corp. (PHIO) - Business Model: Revenue Streams

Potential Licensing Agreements

As of Q4 2023, Phio Pharmaceuticals has no active licensing agreements generating revenue.

Research Collaboration Funding

Year Research Collaboration Revenue
2022 $0
2023 $0

Future Therapeutic Product Sales

Current product pipeline remains pre-revenue, with no therapeutic products commercially available.

Intellectual Property Monetization

  • Total patents held: 45
  • Patent families: 8
  • Current IP valuation: Undisclosed

Grant and Government Research Funding

Funding Source Amount Year
NIH Grants $0 2023
SBIR Grants $0 2023

Total Revenue for 2023: $0


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