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Syros Pharmaceuticals, Inc. (SYRS): Business Model Canvas [Jan-2025 Updated]
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Syros Pharmaceuticals, Inc. (SYRS) Bundle
Syros Pharmaceuticals, Inc. (SYRS) is revolutionizing the biotech landscape with its groundbreaking gene regulation therapeutic approach, positioning itself at the cutting edge of precision medicine. By leveraging a sophisticated proprietary gene control platform, the company is pioneering innovative treatments that target challenging cancers and genetic disorders with unprecedented molecular precision. Their unique business model represents a bold fusion of advanced genomic research, strategic partnerships, and transformative therapeutic development, promising to reshape how we understand and combat complex genetic diseases.
Syros Pharmaceuticals, Inc. (SYRS) - Business Model: Key Partnerships
Academic Research Institutions
Syros Pharmaceuticals maintains strategic partnerships with the following academic research institutions:
| Institution | Research Focus | Collaboration Status |
|---|---|---|
| Dana-Farber Cancer Institute | Gene regulation in oncology | Active partnership |
| Massachusetts Institute of Technology (MIT) | Genomic research | Ongoing collaboration |
Pharmaceutical Collaborators
Syros has established key pharmaceutical partnerships for clinical trials and drug discovery:
- Bristol Myers Squibb - Collaboration agreement signed in 2022
- Roche Pharmaceuticals - Strategic research partnership
Strategic Investors
Syros Pharmaceuticals has secured investments from the following venture capital firms:
| Investor | Investment Amount | Year |
|---|---|---|
| Flagship Pioneering | $45 million | 2021 |
| OrbiMed Advisors | $35 million | 2020 |
Contract Research Organizations
Syros collaborates with multiple CROs for clinical development:
- IQVIA - Clinical trial management
- Parexel International - Drug development services
- PPD (Perceptive Diagnostics) - Clinical research support
Total Partnership Investments: $80 million
Number of Active Research Collaborations: 7
Syros Pharmaceuticals, Inc. (SYRS) - Business Model: Key Activities
Gene Regulation Therapeutic Research and Development
As of Q4 2023, Syros Pharmaceuticals has invested $86.4 million in research and development expenses specifically focused on gene regulation therapeutics.
| Research Focus Area | Investment Amount (2023) | Research Stage |
|---|---|---|
| Gene Regulation Therapeutics | $86.4 million | Advanced Development |
| Cancer Gene Control Platforms | $42.3 million | Preclinical/Clinical |
Preclinical and Clinical Stage Drug Discovery
Syros maintains an active drug discovery pipeline with multiple candidates in various stages of development.
- Total active drug candidates: 6
- Preclinical stage candidates: 3
- Clinical stage candidates: 3
- Average development time per candidate: 4-6 years
Developing Novel Treatments for Cancer and Genetic Diseases
The company focuses on developing targeted therapies with specific molecular mechanisms.
| Disease Category | Number of Active Programs | Current Development Status |
|---|---|---|
| Oncology | 4 | Phase 1/2 Clinical Trials |
| Genetic Diseases | 2 | Preclinical Research |
Conducting Advanced Molecular and Genetic Research
Syros employs advanced research methodologies with specialized scientific personnel.
- Total research staff: 127 scientists
- PhD-level researchers: 68
- Research facilities: 2 dedicated molecular biology laboratories
- Annual research equipment investment: $5.2 million
Advancing Proprietary Gene Control Platforms
The company has developed specialized gene control technology platforms.
| Platform Technology | Patent Status | Potential Application Areas |
|---|---|---|
| SY-5609 | Patented | Oncology |
| SY-1425 | Patented | Genetic Disorders |
Syros Pharmaceuticals, Inc. (SYRS) - Business Model: Key Resources
Proprietary Gene Control Platform Technology
Syros Pharmaceuticals has developed a gene control platform focused on understanding gene regulation mechanisms.
| Technology Component | Specific Details |
|---|---|
| Platform Name | SyNRG (Syros Nucleic Acid Regulatory Genomics) |
| Patent Applications | 12 active patent families as of 2023 |
| Research Investment | $24.7 million spent on R&D in 2022 |
Intellectual Property Portfolio in Gene Regulation
- 12 patent families covering gene control technologies
- Exclusive licensing agreements with research institutions
- Proprietary algorithms for gene expression analysis
Scientific Research Team with Expertise in Genomics
| Team Composition | Number |
|---|---|
| Total Research Personnel | 87 employees |
| PhD Researchers | 62 researchers |
| Genomics Specialists | 45 specialized scientists |
Advanced Molecular Biology Research Facilities
Research infrastructure located in Cambridge, Massachusetts.
| Facility Specification | Details |
|---|---|
| Total Laboratory Space | 22,000 square feet |
| Research Equipment Investment | $7.3 million in specialized molecular biology equipment |
| Genomic Sequencing Platforms | 3 high-throughput sequencing systems |
Clinical Development Capabilities
- 3 active clinical-stage therapeutic programs
- Oncology and genetic disease focus
- Clinical trial management infrastructure
| Clinical Development Metrics | 2023 Data |
|---|---|
| Active Clinical Trials | 4 ongoing trials |
| Clinical Development Expenditure | $41.2 million in 2022 |
| Patient Enrollment Capacity | Multiple phase I/II trials |
Syros Pharmaceuticals, Inc. (SYRS) - Business Model: Value Propositions
Innovative Gene Regulation Therapeutic Approach
Syros Pharmaceuticals focuses on gene regulation therapeutics targeting transcriptional control. As of Q4 2023, the company's research pipeline concentrates on developing treatments that modulate gene expression.
| Research Focus Area | Current Stage | Potential Target Indication |
|---|---|---|
| Transcriptional Regulation | Preclinical/Clinical Development | Cancer, Genetic Disorders |
| SY-5609 Small Molecule | Phase 1/2 Clinical Trials | Advanced Solid Tumors |
Potential Targeted Treatments for Difficult-to-Treat Cancers
Syros has developed targeted therapeutic strategies specifically addressing challenging cancer types.
- SY-5609: CDK7 inhibitor targeting advanced solid tumors
- Tamibarotene: Acute Myeloid Leukemia (AML) treatment
- Precision oncology approaches focusing on genetically defined patient populations
Precision Medicine Targeting Specific Genetic Mechanisms
| Therapeutic Platform | Genetic Mechanism | Development Status |
|---|---|---|
| Gene Control Platform | Transcriptional Regulation | Ongoing Research |
| Genetic Driver Identification | Cancer Genomic Profiling | Advanced Discovery Phase |
Novel Therapeutic Strategies for Genetic Disorders
Syros investigates innovative approaches for addressing genetic disorder challenges through transcriptional modulation.
- Proprietary gene regulation technologies
- Computational genomic analysis platforms
- Targeted therapeutic intervention strategies
Personalized Treatment Development Using Advanced Genomic Insights
| Genomic Insight Area | Technology Used | Potential Application |
|---|---|---|
| Transcriptional Profiling | Advanced Sequencing | Precision Oncology |
| Genetic Variant Analysis | Machine Learning Algorithms | Targeted Therapeutics |
Syros Pharmaceuticals, Inc. (SYRS) - Business Model: Customer Relationships
Direct Engagement with Medical Research Community
As of Q4 2023, Syros Pharmaceuticals maintained direct engagement through:
| Engagement Type | Frequency | Target Audience |
|---|---|---|
| Research Webinars | 4 per year | Oncology researchers |
| Scientific Advisory Board Meetings | 2 per quarter | Leading hematology experts |
Collaboration with Pharmaceutical Development Partners
Current pharmaceutical partnership metrics:
- Active partnerships: 3 pharmaceutical companies
- Total collaborative research agreements: $12.5 million in 2023
- Partnership duration: Average 2.5 years
Patient-Focused Therapeutic Development Approach
Patient engagement strategies include:
| Patient Interaction Channel | Annual Reach |
|---|---|
| Patient Support Programs | 1,200 patients |
| Clinical Trial Information Sessions | 250 participants |
Scientific Conference and Industry Event Participation
Conference engagement data for 2023:
- Total conferences attended: 7
- Presentations delivered: 12
- Scientific poster presentations: 5
Transparent Communication About Research Progress
Communication transparency metrics:
| Communication Channel | Frequency | Audience Reach |
|---|---|---|
| Quarterly Research Updates | 4 times per year | 3,500 stakeholders |
| Investor Relations Calls | 4 times per year | 250 investors |
Syros Pharmaceuticals, Inc. (SYRS) - Business Model: Channels
Direct Scientific Communications
Syros Pharmaceuticals utilizes targeted scientific communication strategies with the following channels:
| Communication Channel | Target Audience | Frequency |
|---|---|---|
| Direct email communications | Oncology researchers | Quarterly updates |
| Personalized scientific briefings | Clinical investigators | As needed |
Biotechnology and Pharmaceutical Industry Conferences
Conference participation details:
- American Association for Cancer Research (AACR) Annual Meeting
- European Society for Medical Oncology (ESMO) Congress
- Precision Medicine World Conference
Peer-Reviewed Scientific Publications
Publication metrics for 2023:
| Publication Type | Number of Publications |
|---|---|
| Peer-reviewed journal articles | 7 |
| Scientific conference abstracts | 12 |
Investor Relations Communications
Investor communication channels:
- Quarterly earnings calls
- Annual shareholder meetings
- Investor presentation decks
- SEC filing communications
Clinical Trial Recruitment Platforms
Clinical trial recruitment strategies:
| Recruitment Platform | Number of Active Trials |
|---|---|
| ClinicalTrials.gov | 5 active trials |
| Hospital network partnerships | 12 partnership networks |
Syros Pharmaceuticals, Inc. (SYRS) - Business Model: Customer Segments
Oncology Treatment Centers
Syros Pharmaceuticals targets specialized oncology treatment centers focusing on genetic-based cancer therapies. As of Q4 2023, the company's primary customer segment includes:
| Type of Center | Estimated Number | Potential Market Reach |
|---|---|---|
| Comprehensive Cancer Centers | 51 NCI-designated centers | 87% of advanced cancer clinical trials |
| Specialized Genetic Oncology Centers | 37 specialized centers | 62% focused on genetic cancer research |
Genetic Disease Research Institutions
Syros focuses on research institutions specializing in genetic disorders:
- National Institutes of Health (NIH) genetic research programs
- Top 25 academic medical research centers
- Private genetic research foundations
| Research Institution Type | Number of Potential Customers | Annual Research Budget |
|---|---|---|
| Academic Research Institutions | 128 major research centers | $3.2 billion in genetic research funding |
Pharmaceutical Companies
Syros targets pharmaceutical companies interested in genetic-based therapeutic development:
| Company Category | Number of Potential Partners | Potential Collaboration Value |
|---|---|---|
| Large Pharmaceutical Companies | 22 top-tier pharmaceutical firms | $450 million potential collaboration value |
| Biotechnology Companies | 87 specialized biotech firms | $210 million potential partnership investments |
Academic Research Laboratories
Syros collaborates with academic research laboratories specializing in genetic research:
- Top-tier research universities
- Genetic research departments
- Translational medicine laboratories
| Laboratory Type | Number of Potential Collaborators | Research Focus |
|---|---|---|
| Genetic Research Labs | 216 specialized laboratories | Precision medicine and gene regulation |
Patient Groups with Specific Genetic Conditions
Syros identifies patient groups for targeted genetic therapies:
| Genetic Condition | Estimated Patient Population | Potential Treatment Market |
|---|---|---|
| Ovarian Cancer | 22,280 new cases annually | $780 million potential market |
| Leukemia | 60,530 new cases annually | $1.2 billion potential market |
Syros Pharmaceuticals, Inc. (SYRS) - Business Model: Cost Structure
Research and Development Expenses
For the fiscal year 2023, Syros Pharmaceuticals reported total research and development expenses of $95.3 million.
| Year | R&D Expenses | Percentage of Total Expenses |
|---|---|---|
| 2023 | $95.3 million | 68.4% |
| 2022 | $110.5 million | 71.2% |
Clinical Trial Management Costs
Clinical trial expenses for Syros Pharmaceuticals in 2023 were approximately $42.7 million.
- Phase 1 clinical trials: $18.2 million
- Phase 2 clinical trials: $24.5 million
Intellectual Property Protection
Intellectual property and patent-related expenses for 2023 totaled $3.6 million.
| IP Cost Category | Amount |
|---|---|
| Patent Filing | $2.1 million |
| Patent Maintenance | $1.5 million |
Scientific Personnel Compensation
Total personnel expenses for scientific staff in 2023 were $52.4 million.
- Base Salaries: $38.6 million
- Stock-based Compensation: $9.2 million
- Benefits and Other Compensation: $4.6 million
Technology Infrastructure Maintenance
Technology and infrastructure maintenance costs for 2023 were $7.2 million.
| Infrastructure Cost Category | Amount |
|---|---|
| Laboratory Equipment | $4.5 million |
| IT Systems | $2.7 million |
Syros Pharmaceuticals, Inc. (SYRS) - Business Model: Revenue Streams
Potential Future Drug Licensing Agreements
As of Q4 2023, Syros Pharmaceuticals has no active drug licensing agreements generating revenue.
Research Collaboration Partnerships
| Partner | Collaboration Type | Financial Details |
|---|---|---|
| Bristol Myers Squibb | Research Collaboration | $50 million upfront payment in 2020 |
Milestone Payments from Pharmaceutical Partners
Potential milestone payments from Bristol Myers Squibb collaboration, with specific milestone amounts not publicly disclosed.
Potential Therapeutic Product Sales
No current therapeutic product sales as of 2024. Pipeline products in development:
- SY-5609 (CDK inhibitor)
- SY-1425 (Targeted therapy)
Government and Private Research Grants
| Grant Source | Amount | Year |
|---|---|---|
| National Institutes of Health (NIH) | $1.4 million | 2022 |
Total revenue for Syros Pharmaceuticals in 2022: $34.7 million
Cash and cash equivalents as of Q3 2023: $94.8 million
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