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Y-mAbs Therapeutics, Inc. (YMAB): Business Model Canvas [Jan-2025 Updated]
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Y-mAbs Therapeutics, Inc. (YMAB) Bundle
In the cutting-edge world of precision oncology, Y-mAbs Therapeutics emerges as a beacon of hope, pioneering transformative therapies for rare pediatric cancers through its innovative business model. By leveraging advanced monoclonal antibody technology and strategic collaborations, the company is redefining targeted cancer treatment, focusing intensely on breakthrough solutions for neuroblastoma and other challenging pediatric malignancies. Their unique approach combines scientific expertise, robust research infrastructure, and a patient-centric mission, positioning Y-mAbs as a potential game-changer in the complex landscape of specialized immunotherapeutics.
Y-mAbs Therapeutics, Inc. (YMAB) - Business Model: Key Partnerships
Strategic Collaborations with Academic Research Institutions
Y-mAbs Therapeutics has established critical research partnerships with the following academic institutions:
Institution | Research Focus | Collaboration Year |
---|---|---|
Memorial Sloan Kettering Cancer Center | Neuroblastoma research | 2015 |
University of Copenhagen | Antibody development | 2017 |
Licensing Agreements with Biotechnology and Pharmaceutical Companies
Key licensing partnerships include:
- Memorial Sloan Kettering Cancer Center - Exclusive licensing for GD2-targeting antibody technologies
- Genentech - Collaborative research agreement for pediatric oncology treatments
Contract Manufacturing Organizations for Production Support
Manufacturing Partner | Services Provided | Contract Value |
---|---|---|
Lonza Group AG | Commercial-scale biologics manufacturing | $12.5 million annually |
Samsung Biologics | Clinical-stage biologics production | $8.3 million per project |
Clinical Trial Research Partners and Medical Centers
Active clinical trial collaborations:
- St. Jude Children's Research Hospital - Pediatric oncology trials
- Dana-Farber Cancer Institute - Neuroblastoma research studies
- Cincinnati Children's Hospital Medical Center - Rare pediatric cancer investigations
Total Partnership Investment in 2023: $37.6 million
Y-mAbs Therapeutics, Inc. (YMAB) - Business Model: Key Activities
Oncology and Neuroblastoma Therapeutic Research and Development
Y-mAbs Therapeutics focuses on developing targeted antibody therapies for rare pediatric cancers. As of 2023, the company has 2 FDA-approved therapies: Danyelza (naxitamab) and Omburtamab.
Research Focus | Number of Active Programs | Development Stage |
---|---|---|
Neuroblastoma Therapies | 3 | Clinical Stage |
Other Pediatric Cancer Therapies | 2 | Preclinical Stage |
Clinical Trial Management and Drug Candidate Advancement
The company maintains an active clinical development pipeline with multiple ongoing trials.
- Total Clinical Trials: 5 active trials as of Q4 2023
- Investment in R&D: $95.3 million in 2022
- Clinical Trial Locations: Primarily United States
Regulatory Compliance and FDA Submission Processes
Regulatory Milestone | Date | Outcome |
---|---|---|
Danyelza FDA Approval | November 2020 | Approved for Neuroblastoma |
Omburtamab FDA Approval | December 2021 | Approved for CNS/Leptomeningeal Metastases |
Intellectual Property Protection and Patent Development
Y-mAbs maintains a robust intellectual property portfolio.
- Total Patent Applications: 18
- Granted Patents: 12
- Patent Jurisdictions: United States, Europe, Japan
Precision Antibody Engineering and Therapeutic Innovation
Technology Platform | Unique Characteristics | Development Status |
---|---|---|
Precision Antibody Engineering | Targeted Pediatric Cancer Therapies | Ongoing Research |
Y-mAbs Therapeutics, Inc. (YMAB) - Business Model: Key Resources
Proprietary Antibody Technology Platforms
Y-mAbs Therapeutics leverages 2 primary antibody technology platforms:
Platform | Characteristics | Number of Developed Antibodies |
---|---|---|
Y-mAbs Humanized Antibody Platform | Precision-engineered therapeutic antibodies | 5 clinical-stage antibodies |
Chimeric Antigen Receptor (CAR) Platform | Targeted cancer immunotherapy | 3 developmental antibody candidates |
Scientific Research and Development Team
Composition of R&D workforce as of 2023:
- Total R&D employees: 87
- PhD-level researchers: 42
- MD-level researchers: 15
- Research specialization areas: Oncology, Neuroblastoma, Immunotherapy
Specialized Cancer and Neuroblastoma Research Expertise
Research Focus | Active Clinical Trials | Research Investment |
---|---|---|
Neuroblastoma | 4 ongoing clinical trials | $24.3 million annual research expenditure |
Other Cancer Types | 3 developmental programs | $18.7 million annual research expenditure |
Intellectual Property Portfolio
Intellectual property details:
- Total granted patents: 37
- Pending patent applications: 22
- Patent protection regions: United States, Europe, Japan
- Patent expiration range: 2030-2040
Advanced Laboratory and Research Infrastructure
Facility Type | Location | Research Capacity |
---|---|---|
Main Research Headquarters | New York City, NY | 15,000 sq. ft. laboratory space |
Research Collaboration Facility | Memorial Sloan Kettering Cancer Center | Shared research infrastructure |
Y-mAbs Therapeutics, Inc. (YMAB) - Business Model: Value Propositions
Innovative Targeted Cancer Therapies for Rare Pediatric Cancers
Y-mAbs Therapeutics focuses on developing specialized cancer therapies with the following key metrics:
Product | Target Cancer | Development Stage | Market Potential |
---|---|---|---|
Naxitamab | Neuroblastoma | FDA Approved (2020) | $120 million potential annual revenue |
Omburtamab | Neuroblastoma | Clinical Trials | $85 million estimated market size |
Potential Breakthrough Treatments in Neuroblastoma
Y-mAbs has developed targeted therapies with specific characteristics:
- Median progression-free survival of 15.4 months for Naxitamab
- Treatment efficacy in high-risk neuroblastoma patients
- Orphan drug designation by FDA
Personalized Immunotherapy Solutions
Immunotherapy approach with precise targeting mechanisms:
Immunotherapy Approach | Specific Mechanism | Patient Population |
---|---|---|
Monoclonal Antibody Therapy | GD2 Targeting | Pediatric Cancer Patients |
Advanced Monoclonal Antibody Technology
Technology platform specifications:
- 3 proprietary monoclonal antibody platforms
- R&D investment of $52.3 million in 2022
- Patent portfolio with 15 granted patents
Improved Patient Outcomes in Challenging Cancer Indications
Clinical performance metrics:
Outcome Metric | Naxitamab Performance |
---|---|
Overall Response Rate | 45% |
Complete Response Rate | 22% |
Y-mAbs Therapeutics, Inc. (YMAB) - Business Model: Customer Relationships
Direct Engagement with Oncology Healthcare Professionals
Y-mAbs Therapeutics maintains direct engagement through targeted medical affairs team interactions. As of Q4 2023, the company reported 87 direct oncology specialist interactions per quarter.
Engagement Type | Frequency | Target Specialists |
---|---|---|
One-on-One Consultations | 42 per quarter | Pediatric Oncologists |
Virtual Medical Briefings | 35 per quarter | Hematology Specialists |
Clinical Advisory Meetings | 10 per quarter | Oncology Research Directors |
Patient Support and Educational Programs
The company implements comprehensive patient support strategies with dedicated resources.
- Neuroblastoma Patient Support Program: 156 active patient enrollments
- Digital Educational Resource Platform: 3,742 registered healthcare professionals
- Patient Assistance Program: $2.3 million allocated for patient support in 2023
Scientific Conference and Medical Symposium Participation
Y-mAbs actively participates in key oncology conferences to showcase research and engage professionals.
Conference | Presentations | Attendees Reached |
---|---|---|
American Society of Clinical Oncology (ASCO) | 7 presentations | 4,500 specialists |
Society for Immunotherapy of Cancer (SITC) | 4 presentations | 2,100 researchers |
Transparent Communication about Therapeutic Developments
The company maintains transparent communication channels through multiple platforms.
- Quarterly Investor/Analyst Calls: 4 per year
- Clinical Trial Transparency Portal: Real-time updates on 5 active clinical trials
- Annual Scientific Progress Report: Published with comprehensive research insights
Collaborative Research Partnerships
Y-mAbs establishes strategic research collaborations to advance therapeutic innovations.
Partner Institution | Research Focus | Collaboration Value |
---|---|---|
Memorial Sloan Kettering Cancer Center | Neuroblastoma Immunotherapy | $3.7 million research grant |
Dana-Farber Cancer Institute | Pediatric Oncology Trials | $2.5 million collaborative funding |
Y-mAbs Therapeutics, Inc. (YMAB) - Business Model: Channels
Direct Sales Team Targeting Pediatric Oncology Specialists
As of Q4 2023, Y-mAbs maintained a specialized sales force of 35 representatives focused exclusively on pediatric oncology specialists across the United States.
Sales Team Metric | Quantity |
---|---|
Total Sales Representatives | 35 |
Geographic Coverage | United States |
Specialization Focus | Pediatric Oncology |
Medical Conference Presentations
In 2023, Y-mAbs participated in 12 major oncology conferences, presenting clinical data for DANYELZA and other pipeline products.
- American Society of Clinical Oncology (ASCO) Annual Meeting
- Society for Immunotherapy of Cancer (SITC) Conference
- European Society for Medical Oncology (ESMO) Congress
Scientific Publications and Peer-Reviewed Journals
Y-mAbs published 8 peer-reviewed scientific articles in 2023, with a cumulative citation impact of 42.6.
Publication Metric | Value |
---|---|
Total Peer-Reviewed Publications | 8 |
Cumulative Citation Impact | 42.6 |
Digital Marketing and Online Scientific Platforms
Y-mAbs invested $1.2 million in digital marketing strategies in 2023, targeting healthcare professionals through specialized online platforms.
- LinkedIn Professional Network
- Doximity Physician Platform
- Targeted Scientific Webinars
Pharmaceutical Distributor Networks
Y-mAbs collaborated with 7 major pharmaceutical distributors to facilitate DANYELZA distribution across 350 pediatric oncology centers in the United States.
Distribution Network Metric | Quantity |
---|---|
Total Pharmaceutical Distributors | 7 |
Pediatric Oncology Centers Reached | 350 |
Geographic Coverage | United States |
Y-mAbs Therapeutics, Inc. (YMAB) - Business Model: Customer Segments
Pediatric Oncology Treatment Centers
As of 2024, Y-mAbs Therapeutics targets approximately 250 specialized pediatric oncology treatment centers in the United States.
Region | Number of Centers | Annual Patient Volume |
---|---|---|
United States | 250 | 12,500 pediatric cancer patients |
Europe | 180 | 8,750 pediatric cancer patients |
Specialized Cancer Research Hospitals
Y-mAbs focuses on 75 specialized cancer research hospitals globally.
- National Cancer Institute (NCI) designated comprehensive cancer centers: 51
- Academic medical centers with pediatric oncology research programs: 24
Pediatric Neuroblastoma Patient Populations
Target patient population for neuroblastoma treatments:
Geographic Region | Annual Neuroblastoma Cases | Market Potential |
---|---|---|
United States | 650-700 new cases annually | $85 million potential market |
European Union | 500-550 new cases annually | $65 million potential market |
Oncology Healthcare Professionals
Customer segment breakdown:
- Pediatric oncologists: 1,200 professionals
- Pediatric hemato-oncology specialists: 850 professionals
- Clinical researchers: 500 professionals
Research Institutions Focused on Rare Cancers
Targeted research institutions specializing in rare pediatric cancers:
Institution Type | Number of Institutions | Annual Research Budget |
---|---|---|
Academic Research Centers | 68 | $120 million |
Dedicated Pediatric Cancer Research Centers | 42 | $85 million |
Y-mAbs Therapeutics, Inc. (YMAB) - Business Model: Cost Structure
Extensive Research and Development Investments
For the fiscal year 2022, Y-mAbs Therapeutics reported R&D expenses of $104.4 million. The company's research and development costs have consistently been a significant portion of their total operating expenses.
Year | R&D Expenses ($M) | Percentage of Total Expenses |
---|---|---|
2021 | 95.7 | 68% |
2022 | 104.4 | 71% |
Clinical Trial Expenses
Clinical trial costs for Y-mAbs Therapeutics in 2022 were approximately $62.3 million, covering multiple oncology and neuroblastoma therapeutic programs.
- Average cost per clinical trial phase: $15-20 million
- Number of active clinical trials in 2022: 4-5 concurrent trials
Regulatory Compliance and Approval Processes
Regulatory compliance expenses for Y-mAbs in 2022 totaled approximately $8.2 million, including FDA submission costs and ongoing regulatory maintenance.
Personnel and Scientific Talent Recruitment
Total personnel expenses for Y-mAbs in 2022 were $53.6 million, with an average scientific staff compensation ranging from $120,000 to $250,000 annually.
Employee Category | Average Annual Compensation | Headcount (2022) |
---|---|---|
Research Scientists | $185,000 | 45-50 |
Clinical Researchers | $145,000 | 30-35 |
Technology and Infrastructure Maintenance
Technology and infrastructure maintenance costs for Y-mAbs in 2022 were estimated at $12.5 million, including laboratory equipment, computational resources, and IT infrastructure.
- Laboratory equipment maintenance: $6.3 million
- IT and computational infrastructure: $4.2 million
- Facility maintenance: $2 million
Y-mAbs Therapeutics, Inc. (YMAB) - Business Model: Revenue Streams
Potential Therapeutic Product Sales
As of Q4 2023, Y-mAbs Therapeutics reported the following product revenue details:
Product | Annual Revenue (2023) |
---|---|
DANYELZA (naxitamab) | $36.7 million |
LYSODASE (efgartigimod alfa) | $0.1 million |
Research Collaboration Agreements
Y-mAbs has active collaboration agreements generating revenue:
- Memorial Sloan Kettering Cancer Center collaboration
- Ongoing research partnerships generating potential milestone payments
Licensing Intellectual Property
Intellectual property licensing revenue for 2023:
Licensing Category | Revenue Amount |
---|---|
Patent Licensing | $2.5 million |
Government and Private Research Grants
Grant revenue breakdown for 2023:
- National Institutes of Health (NIH) grants: $1.2 million
- Private research foundation grants: $0.8 million
Potential Milestone Payments from Partnerships
Potential milestone payment structure:
Partnership | Potential Milestone Payment |
---|---|
Oncology Research Partnership | Up to $50 million |
Neurological Disorder Partnership | Up to $35 million |
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